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A. A. Uwakwe

Publications (3)

Effect of Ethanol Extract of the Fruiting Bodies of Pleurotus Ostreatus on Serum Lipid Profile and Atherogenic Indices of HS-HFD-STZ Induced Diabetic Rats

P. N. Okoroh, Sam Onuoha, A. A. Uwakwe & C. Y. Ukegbu · Asian Journal of Research in Biochemistry · 2021

The effect of ethanol extract of the fruiting bodies of Pleurotus ostreatus on serum lipid profile  and atherogenic indices of high sucrose high fat diet streptozotocin (HS-HFD-STZ) induced diabetic rats was determined by standard methods. All the groups were fed high sucrose-hig...

Open access Research Article 10.9734/ajrb/2021/v9i230196

Inhibition of Phosphodiesterase 5 Enzyme by Pterine- 6 Carboxylic Acid from Baphia nitida –Related to Erectile Dysfunction: Computational Kinetic

Wopara, Iheanyichukwu, S. K. Mobisson, Egelege Aziemeola Pius, A. A. Uwakwe & M. O. Wegwu · European Journal of Medicinal Plants · 2020

Treatment of erectile dysfunction is associated with inhibition of Phosphodiesterase 5 enzyme. This study deals with the evaluation of Pterin-6-carboxylic acid inhibitory activity on phosphodiesterase 5 (PDB ID: 4OEW) using in silico docking studies. Pterin-6-carboxylic acid from...

Open access Research Article 10.9734/ejmp/2020/v31i430231

Kolaviron an Active Biflavonoid of Garcinia kola Extract Prevent 1,2-dimethylhydrazine Induced Oxidative Stress and Lipid Peroxidation in the Initiation Phase of Colon Carcinogenesis in Wistar Rats

A. S. Eboh, D. Ere, L. C. Chuku & A. A. Uwakwe · Journal of Cancer and Tumor International · 2015

Colon cancer is steadily increasing in Africa with high mortality and it is a pathological consequence of persistent oxidative stress. Kolaviron an active biflavonoid, has been shown to possess antioxidant, anti-lipid peroxidation and chemopreventive properties. The present study...

Open access Research Article 10.9734/JCTI/2015/16809