Introduction: Taxanes and anthracyclin containing regimes are the most successful regimens in advanced gastric cancer with comparable results but with different toxicity profiles. Objective: To compare efficacy and toxicity of 2 regimens one containing anthrathycline (ECSF regime...
Open access
Research Article10.9734/JCTI/2017/32058
Background: Wilms’ tumor (WT1) gene expression has been reported in the majority of acute leukemia patients at diagnosis and has been evaluated as a prognostic and minimal residual disease (MRD) marker but its role is still controversial. Methods: Real-time quantitative polymeras...
Open access
Research Article10.9734/BJMMR/2015/15834
Introduction and Aim of the Work: The ABC (ATP-binding cassette) transporter family contributes to the multidrug resistance the genetic variants of this gene have been intensively studied so far. Some single nucleotide polymorphism (SNPs) of ABCB1 has a correlation with the risk...
Aim: To search for JAK2V617F mutation in patients with acute myeloid and acute lymphoblastic leukemia in south Egypt. Study Design: JAK2V617F mutation detected by amplification refractory mutation system (ARMS) -PCR. Place and Duration of Study: Department of clinical pathology a...
Open access
Research Article10.9734/IBRR/2014/5340
Introduction and Aim of the Work: Telomeres ensure genome integrity during replication. Loss of telomeric function leads to cell immortalization, accumulation of genetic alterations and tumorigenesis. Telomere length (TL) in previous studies in breast cancer patients suggested th...
Background: High dose chemotherapy with autologous stem cell transplantation (ASCT) is the standard of care and commonly used procedure for patients with relapsed non Hodgkin lymphomas (NHL). There is no clear evidence of superior conditioning regimen and studies that comparing d...
Open access
Research Article10.9734/IBRR/2017/35556
Background: Several studies investigated the miRNAs in cancer trying to assess the prognosis or to predict the response to certain treatment .One of these miRNAs are miR 125b , it was suggested by previous results as a good marker for prediction of aromatase inhibitors (AI) respo...
Open access
Research Article10.9734/jcti/2020/v10i330127