Andrea Cuschieri

α-Solanine Suppresses Glioblastoma Multiforme Growth and Metastatic Properties by Modulating the Apoptosis-autophagy Axis

Andrea Cuschieri & Byron Baron · Journal of Pharmaceutical Research International · 2023

Introduction: Glioblastoma multiforme (GBM) has a poor prognosis despite optimal treatment. Recent studies have shown the potential of phytochemicals as anti-cancer agents. α-solanine, derived from plants of the Solanum genus, is a promising molecule in this regard. This study in...

Open access Research Article 10.9734/jpri/2023/v35i207402

Glioblastoma Multiforme: Molecular Biology and Updated Systematic Review on Natural Extract and Phytochemical Efficacy In-vitro

Andrea Cuschieri & Byron Baron · Journal of Complementary and Alternative Medical Research · 2023

Glioblastoma multiforme (GBM) is the most prevalent primary malignant central nervous system tumours (CNST). Current treatment consists of surgical resection and adjuvant chemoradiotherapy, the gold-standard agent being Temozolomide (TMZ). Despite optimal treatment, GBM has an ab...

Open access Research Article 10.9734/jocamr/2023/v21i1427