Ankit Anand Kharia

Development and Evaluation of Extended Release Tacrolimus Tablets by Melt Granulation in Combination with Magnesium Alumino Metasilicate

Asif Anwar, Priyanka Soni & Ankit Anand Kharia · Journal of Pharmaceutical Research International · 2021

To increase the effectiveness of tacrolimus, the present study sought to develop extended-release tablets. It is used to treat mild to severe atopic dermatitis as well as to prevent organ rejection after organ transplantation. Tacrolimus, on the other hand, has a poor bioavailabi...

Open access Research Article 10.9734/jpri/2021/v33i64B35978

Controlled Release Formulation of Tofacitinib Citrate Tablets Evaluated Using Quality by Design (QBD) Approach

Satyabrata Barik, Priyanka Soni & Ankit Anand Kharia · Journal of Pharmaceutical Research International · 2021

The goal of the project is to use the quality-by-design (QbD) method to create and optimise Tofacitinib citrate matrix tablets with controlled release excipients. The drug's physicochemical parameters, reference product characterisation, QTPP (Quality Target Product Profile), and...

Open access Research Article 10.9734/jpri/2021/v33i64A35688