Anthonia Oshaye Uku

Polyvinyl Chloride Exposure Induces Liver Injury: A Biochemical and Histological Evaluation

Vincent-Junior Onoriode Igben, Anthony Taghogho Eduviere, Emuesiri Umukoro, Blessing Oghenekparobor Elijah & Anthonia Oshaye Uku · Asian Journal of Advanced Research and Reports · 2025

Objective: Microplastics are ubiquitous in our environment, with evidence of its presence in various body tissues, however the extent of its toxicity at low dose from chronic administration and bioaccumulation in humans remains unknown. This study aims at evaluating the toxicolog...

Open access Research Article 10.9734/ajarr/2025/v19i81115

Attenuation of Induced Oxidative Stress and Neurological Deficit in Tramadol Use by Co-administration with Ribena Drink and Vitamin E in Male Wistar Rats

Igben Onoriode Vincent_Junior, Isibor Anwuli Promise, Okoro Ogheneyebrorue Godswill, Isioma Cynthia Nwaokoro, Obohwemu Oberhiri Kennedy, Kaine Omashim Oluwakemi, Egwunyenga Michael Oge, George Kelvin Nkem, Nicholas Asiwe, Osadjere Oghenekevwe Sonia, Obie Rukevwe, Anthonia Oshaye Uku, John Chinedu Obianke & Eboka Olisaemeka Ifechukwude · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2025

Tramadol appears to exert its analgesic effect by binding to the μ‑opioid receptor (MOR) and modulating the noradrenergic, serotonergic activities as a serotonin‑norepinephrine reuptake inhibitor, and also, gamma‑aminobutyric acid (GABA) ‑ergic system. These multiple effects on d...

Open access Research Article 10.9734/ajrimps/2025/v14i2301