Astrid Wiens

Evaluation of the Effectiveness of Oseltamivir for the Treatment of 2009 Pandemic Influenza A (H1N1)

Luana Lenzi, Mônica H. C. Grochocki, Lineu R. Silva, Astrid Wiens, Angela M. Mello & Roberto Pontarolo · International Journal of TROPICAL DISEASE & Health · 2012

Aims: Evaluate retrospectively the effectiveness of treatment with oseltamivir in a Brazilian subpopulation infected during the 2009 pandemic influenza A(H1N1) and compare drug activity based on the presence or absence of other disease risk factors and also the time from onset of...

Open access Research Article 10.9734/IJTDH/2012/1310

A Critical Appraisal of Clinical Practice Guidelines for Pharmacological Treatments of Paroxysmal Nocturnal Hemoglobinuria

Yara Maria da Silva Pires, Flávia Deffert, Thais Humenhuk, Ana Paula Oliveira Vilela, Aline de Fátima Bonetti & Astrid Wiens · Journal of Advances in Biology & Biotechnology · 2023

Aims: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare chronic disease characterized by complement-mediated hemolysis, thrombosis, and bone marrow failure. This study aims to identify methodological limitations in Clinical Practice Guidelines (CPG) for the treatment of PNH. Th...

Open access Research Article 10.9734/jabb/2023/v26i12668