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Augustine Oluchukwu Asogwa

Publications (5)

Potential Effect of Senna Hirsuta Leaf as Alternative Therapy for Epilepsy and Oxidative Stress

Augustine Oluchukwu Asogwa, Felix Keneolisa Asogwa, Celestine Obiora Ugwu, Jude Ibeabuchi Ali, Raymond Ogbonna Offia, Martins Detu Ikpechukwu & Damian Chukwunonso Mbah · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2025

Epilepsy is a neurological condition that affects the central nervous system and is characterized by strange emotions and actions. Antioxidants are believed to play a very vital role in the body defense system against reactive oxygen species (ROS). ROS, is a basal cause of aging...

Open access Research Article 10.9734/ajrimps/2025/v14i2302

Neurobehavioral and Hematological Effects of Zapoteca portoricensis (Jacq.) H.M.Hern Root Ethylacetate Fraction against Scopolamine Induced Cognitive Impairment in Rats

Felix Keneolisa Asogwa, Augustine Oluchukwu Asogwa, Daniel Lotanna Ajaghaku, Jude Ibeabuchi Ali, Faustina Chidiebere Udeozo & Sylvia Amarachi Ojobor · International Journal of Research and Reports in Hematology · 2026

Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterised by progressive dementia, neuroinflammation, and the accumulation of intracellular neurofibrillary tangles and extracellular amyloid plaques. Oxidative stress and cholinergic dysfunction are key con...

Open access Research Article 10.9734/ijr2h/2026/v9i2244

Neuroprotective Effect of Butanol Fraction of Zapoteca portoricensis (Jacq.) H. M. Hern Root on Scopolamine Induced Memory Impairment in Rats

Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Celestine Obiora Ugwu & Judith Chinyere Ugwu · Asian Journal of Research and Reports in Neurology · 2026

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterised by cognitive decline, memory impairment, and oxidative stress. Aim: This study investigated the neuroprotective effects of the butanol fraction of Zapoteca portoricensis root (BFZP) in...

Open access Research Article 10.9734/ajorrin/2026/v9i1193

Exploring the Potential Impact of the Use of Probiotics on the Pharmacokinetics and the Pharmacodynamics of Drugs: A Narrative Review

Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Celestine Obiora Ugwu, Detu Martins Ikpechukwu, Kingsley Chidiebere Ndu & Linus Odinakachukwu Nsude · International Journal of Pathogen Research · 2025

Probiotics are live microorganisms that, when administered in adequate amounts, confer health benefits to the host. Their impact on drug bioavailability and efficacy, particularly in gastrointestinal disorders, has gained considerable interest. This paper explores how probiotics...

Open access Research Article 10.9734/ijpr/2025/v14i3367

Beyond Dopamine: Exploring Novel Pharmacological Targets for Improved Antipsychotic Outcomes

Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Levi Onyebuchi Idokoja, Detu Martins Ikpechukwu & Damian Chukwunonso Mbah · International Neuropsychiatric Disease Journal · 2025

Schizophrenia is a disorder characterized by a multifaceted pathogenic mechanism impacted by numerous genes. The investigation of its pathophysiology is mostly dominated by the dopamine hypothesis.  Multi-target therapies represent a viable strategy for addressing polygenic disor...

Open access Research Article 10.9734/indj/2025/v22i4492