Brian Churchill

Importance of Glomerular Filtration Rate Determination and its Role in Drug-Dose Adjustments with Special Reference to Oncology

Brian Churchill, Ekaterina Vorozheikina, Anastasiya Vyshenskaya, Cecilia Sison & Luis Mendoza · Journal of Cancer and Tumor International · 2025

Glomerular filtration Rate (GFR) measured in steady state is the best marker of kidney function. Glomerular filtration rate can be determined using exogenous markers like inulin, iothalamate, or iohexol (mGFR), or estimated using endogenous markers like creatinine and cystatin C...

Open access Research Article 10.9734/jcti/2025/v15i1279

Outlook on Genetically Engineered CAR T-Cell Therapies for Solid Tumours

Yana Pautova, Yuri Tolkunov, Luis Mendoza & Brian Churchill · International Research Journal of Oncology · 2021

T-cell-based methods using genetic engineering technology are considered the most advanced treatments in cancer therapy. Chimeric antigen receptor (CAR) T-cell therapy is an innovative immunotherapy wherein autologous T-cells are genetically modified to recognize and destroy canc...

Open access Research Article