Chandra Chiappin Cardoso

Diagnosis of Therapy-related Acute Myeloid Leukemia with t(8;21)(q22;q22.1) after Treatment for Mantle Cell Lymphoma and Oral Squamous Cell Carcinoma

Patrícia Colombo Corrêa, Íris Mattos Santos-Pirath, Chandra Chiappin Cardoso, Camila Mattiolo, Bruno Vieira Dias, Mariana Franzoni Maioral & Maria Claudia Santos-Silva · International Journal of Medical and Pharmaceutical Case Reports · 2019

Aims: We report a rare case of therapy-related AML with t(8;21)(q22;q22.1) that occurred after treatment for mantle cell lymphoma (MCL) and oral squamous cell carcinoma (OSCC). Presentation of Case: A 52 years-old male patient was diagnosed with MCL in leukemic phase. The treatme...

Open access Research Article 10.9734/ijmpcr/2019/v12i230104

Flow Cytometric Detection of CK19-Positive Circulating Tumor Cells in Bone Marrow and Peripheral Blood in Metastatic Breast Cancer: A Case Report

Maria Eduarda Cunha-Silva, Heloísa Zorzi Costa, Íris Mattos Santos-Pirath, Chandra Chiappin Cardoso, Daniella Serafin Couto Vieira & Maria Claudia Santos-Silva · International Journal of Medical and Pharmaceutical Case Reports · 2026

Metastatic breast cancer represents the most advanced stage, where the accurate and rapid identification of neoplastic cells is essential for clinical management and prognostic assessment. Although immunohistochemistry is the gold standard, flow cytometry emerges as a robust and...

Open access Research Article 10.9734/ijmpcr/2026/v19i2489

Immunophenotyping for Diagnosis of Oral Lesions: Is It an Important Tool?

Alessandra Rodrigues de Camargo, Bruna Fischer Duarte, Mariah Luz Lisboa, Chandra Chiappin Cardoso, Etiene de Andrade Munhoz, Daniella Serafin Couto Vieira, Joanita Angela Gonzaga Del Moral, Maria Cláudia Santos- Silva & Liliane Janete Grando · International Journal of Medical and Pharmaceutical Case Reports · 2020

Aims: To report two cases of onco-hematologic diseases diagnosed by oral biopsy and subsequent flow cytometry immunophenotyping. Presentation of Case: Case 1: A 36-year-old woman, HIV +, referred to the Hospital Dentistry Center presenting an extensive, ulcerated and painless les...

Open access Research Article 10.9734/ijmpcr/2020/v13i130112

B-Cell Acute Lymphoblastic Leukemia Associated with Isolated and Recurrent Central Nervous System Relapse with a Novel t(6;19)(q21;p13) Translocation: A Case Report

Heloísa Zorzi Costa, Maria Eduarda Cunha-Silva, Andressa Oliveira Martin Wagner, Íris Mattos Santos-Pirath, Chandra Chiappin Cardoso, Sharbel Weidner Maluf & Maria Claudia Santos-Silva · International Journal of Medical and Pharmaceutical Case Reports · 2026

B-cell acute lymphoblastic leukaemia (B-ALL) is a haematological malignancy characterised by the clonal proliferation of B-lymphoid precursors. Cytogenetic and molecular alterations are central to B-ALL classification and diagnosis according to the 2024 World Health Organization...

Open access Research Article 10.9734/ijmpcr/2026/v19i4527

Investigation of Extracellular Vesicles in Plasma Samples: A Sensitive Method for Analysis

Maria Eduarda Cunha-Silva, Laura Otto Walter, Heloísa Zorzi Costa, Íris Mattos Santos Pirath, Chandra Chiappin Cardoso, Lisandra de Oliveira Silva, João Vitor Steimbach, Ana Carolina Rabello de Moraes & Maria Claudia Santos-Silva · Journal of Advances in Medicine and Medical Research · 2026

Extracellular vesicles (EV) are particles enclosed by a lipid bilayer and secreted by various cell types under both normal and pathological conditions. EV secretion plays a key role in maintaining normal physiological functions, while aberrant EV-mediated signaling has been assoc...

Open access Research Article 10.9734/jammr/2026/v38i46112