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Chinwebudu M. Melford

Publications (9)

Clinical and Laboratory Predictors of Severe Leptospirosis, Intensive Care Unit Admission, and Mortality: A Systematic Review of Prognostic Factors

Chinwebudu M. Melford, Jerome A. Tan & Paul Peejay E. Celo · Asian Journal of Research in Infectious Diseases · 2026

Background: Leptospirosis is a zoonotic infection that may range from a mild febrile illness to severe multisystem disease with renal, pulmonary, hepatic, haematological, and haemodynamic complications. Early recognition of patients at risk of severe outcomes is important for tim...

Open access Research Article 10.9734/ajrid/2026/v17i6554

Hantavirus at the Human–rodent Interface: A Global Review and Meta-analysis of Occupational Exposure

Chinwebudu M. Melford, Jerome A. Tan, Paul Peejay E. Celo, Racquel Huerte, Eunice Fay Cayacap, Lorreine Denise W. Castañares & Emmalyn B. Cutamora · Journal of Advances in Microbiology · 2026

Hantaviruses are zoonotic negative-sense RNA viruses transmitted to humans principally through inhalation of aerosolised excreta from persistently infected rodent reservoir hosts. They cause two major clinical syndromes: haemorrhagic fever with renal syndrome (HFRS), predominant...

Open access Research Article 10.9734/jamb/2026/v26i71139

Prevalence and Clinical Significance of Thrombocytopenia in Malaria: A Systematic Review and Meta-analysis

Chinwebudu M. Melford, Kenneth C. Cortes, Patricia Antonette Merecido, Arbee Mae Castro, Fritz Bucao & Eunice Fay Cayacap · International Journal of TROPICAL DISEASE & Health · 2026

Background: Thrombocytopenia is a common hematological abnormality in malaria and has been increasingly recognized as a potential diagnostic and prognostic indicator. However, reported estimates of its prevalence and clinical significance vary widely across studies and settings....

Open access Research Article 10.9734/ijtdh/2026/v47i31734

Nipah Virus Readiness in the Philippines: A National Gap Analysis of Laboratory Diagnostic Capacity, Biosafety Systems and Specimen Referral Networks

Chinwebudu M. Melford, Arbee Mae L. Castro, Patricia Antonette M. Merecido, Anthony Vince P. Bongo, Fritz A. Bucao, Chanelie B. Tabliga & Noelyn N. Fontanoza-Cedonio · International Journal of Pathogen Research · 2026

Nipah virus (NiV) is a high-consequence zoonotic pathogen associated with severe human disease and substantial outbreak risk. Although no sustained transmission has been reported in the Philippines since the 2014 outbreak involving 17 human cases and 9 deaths, ecological evidence...

Open access Research Article 10.9734/ijpr/2026/v15i2440

HIV in the Philippines, 1984–2025: A Longitudinal Analysis of National Surveillance Data and Youth Vulnerability Patterns

Chanelie Bacacao Tabliga & Chinwebudu M. Melford · International Journal of TROPICAL DISEASE & Health · 2026

Background: The Philippines is experiencing one of the fastest-growing HIV epidemics globally, with a substantial rise in cases over the past two decades, particularly among young populations. Understanding long-term epidemiological trends and youth vulnerability is critical for...

Open access Research Article 10.9734/ijtdh/2026/v47i41737

Cumulative Occupational Sunlight Exposure Associated with Oxidative Stress, Thyroid Hormone Alterations and Endocrine Dysregulation among Commercial Motorcycle Riders in a Tropical Setting

Eruotor Ogheneochuko Harrison & Chinwebudu M. Melford · Asian Journal of Research and Reports in Urology · 2026

Commercial motorcycle riders in tropical regions experience prolonged occupational exposure to intense sunlight and heat, which may influence oxidative and endocrine regulation. This study examined the association between cumulative occupational sunlight exposure and oxidative st...

Open access Research Article 10.9734/ajrru/2026/v9i1145

Paradoxical Lipid Patterns and Elevated Atherogenic Risk in HIV Patients on Antiretroviral Therapy from the Rivers State University Teaching Hospital, Nigeria

Tarila Ngowari Aleruchi-Didia, Adline Erinma Ben-Chioma & Chinwebudu M. Melford · International STD Research & Reviews · 2026

Background: Human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) are associated with metabolic disturbances, including dyslipidaemia and increased cardiovascular risk. Aim: This study evaluated lipid profile alterations and atherogenic cardiovascular risk...

Open access Research Article 10.9734/ISRR/2026/v15i1198

In vitro Evaluation of Antibacterial Activity of Persea americana Seed Extract against Pseudomonas aeruginosa

Jerome A. Tan, May Jasmine Eloise A. Ladera, Paul Peejay E. Celo & Chinwebudu M. Melford · International Journal of Pathogen Research · 2026

Antimicrobial resistance among Gram-negative bacteria, particularly Pseudomonas aeruginosa, remains a major public health concern and has prompted increased interest in alternative antimicrobial agents derived from medicinal plants. Persea americana (avocado) seed contains phytoc...

Open access Research Article 10.9734/ijpr/2026/v15i4468

Evaluating the Therapeutic Effects of Aqueous Leaf Extract of Nephrolepis biserrata on Biochemical, Haematological, Physical, Atherogenic and Histopathological Parameters in Testosterone Propionate-Induced Benign Prostatic Hyperplasia in Male Wistar Rats

Eruotor Ogheneochuko Harrison, Ezendiokwere Emmanuel, Okari Karibo Amakiri & Chinwebudu M. Melford · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Benign Prostatic Hyperplasia (BPH) is a common non-cancerous enlargement of the prostate gland, predominantly affecting men over the age of 50 (Kishorebabu et al., 2019). It results from the overgrowth of stromal and smooth muscle cells within the prostate (Mugisha, 2...

Open access Research Article 10.9734/ajrimps/2026/v15i1364