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Detu Martins Ikpechukwu

Publications (2)

Exploring the Potential Impact of the Use of Probiotics on the Pharmacokinetics and the Pharmacodynamics of Drugs: A Narrative Review

Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Celestine Obiora Ugwu, Detu Martins Ikpechukwu, Kingsley Chidiebere Ndu & Linus Odinakachukwu Nsude · International Journal of Pathogen Research · 2025

Probiotics are live microorganisms that, when administered in adequate amounts, confer health benefits to the host. Their impact on drug bioavailability and efficacy, particularly in gastrointestinal disorders, has gained considerable interest. This paper explores how probiotics...

Open access Research Article 10.9734/ijpr/2025/v14i3367

Beyond Dopamine: Exploring Novel Pharmacological Targets for Improved Antipsychotic Outcomes

Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Levi Onyebuchi Idokoja, Detu Martins Ikpechukwu & Damian Chukwunonso Mbah · International Neuropsychiatric Disease Journal · 2025

Schizophrenia is a disorder characterized by a multifaceted pathogenic mechanism impacted by numerous genes. The investigation of its pathophysiology is mostly dominated by the dopamine hypothesis.  Multi-target therapies represent a viable strategy for addressing polygenic disor...

Open access Research Article 10.9734/indj/2025/v22i4492