Objective: Develop and optimize a fast-dissolving oral drug delivery system (ODDS) for Valproic acid (VLA), an anti-epileptic drug, using Design of Experiments (DoE). Methodology: DoE, a powerful tool for optimizing formulations, was employed to investigate the impact of various...
Open access
Research Article10.9734/air/2024/v25i21042
Shiva Kant Thakur, Rahul Pal, Devanand Jha, Prottay Dutta, Prachi Pandey, Bhuneshwar Dutta Tripathi, Mohammad Rizwan, Shradha Ojha, Divya & Ravindra Pal Singh·Journal of Pharmaceutical Research International·2023
Introduction: This study explores the use of Response Surface Methodology (RSM), a statistical optimization technique, to optimize the SR properties of prochlorperazine maleate (PCM) matrix tablets. PCM is a phenothiazine derivative used for treating schizophrenia, nausea, and vo...
Open access
Research Article10.9734/jpri/2023/v35i357483
Objectives: The ongoing research aims to enhance the development of LNH-loaded nanogel by utilizing DoE as the computational method to statistically validate their formulation. Methodology: In this research Chitosan used as a natural polymer and Poly (Ethylene glycol) [PEG] as a...
Open access
Research Article10.9734/air/2023/v24i61009