Dewa Ayu Made Adnyaswari

Effect of Rosemary Leaf Ethanol Extract (Rosmarinus officinalis L.) on Arginase-1 and Tumor Suppressor P53 Expression of Hepatocellular Carcinoma in Male Wistar Strain Rats (Rattus norvegicus L.) Induced By p-Dimethylamino benzaldehyde (DMBA)

Dewa Ayu Made Adnyaswari, Agung Wiwiek Indrayani, I Gusti Ayu Artini, Desak Ketut Ernawati, I Gusti Made Gede Surya Candra Trapika, Ni Putu Sriwidyani & I Gusti Kamasan Nyoman Arijana · Journal of Cancer and Tumor International · 2025

Aims: Tumor Suppressor p53 is a frequent research target to further understand the mechanisms of cancer development and the pathogenesis of cancer. Arginase-1 may also be a potential prognosis predictor for HCC patients, and also be a new target for HCC treatment. This research a...

Open access Research Article 10.9734/jcti/2025/v15i1285

Immunohistochemical Analysis of Tumor Suppressor p53 in p-Dimethylamino Benzaldehyde (DMBA) Induced Hepatocarcinogenesis in Rats (Rattus norvegicus L.) Male Wistar Strains

Dewa Ayu Made Adnyaswari, Agung Wiwiek Indrayani, IGusti Ayu Artini, Desak Ketut Ernawati, I. Gusti Made Gede Surya Candra Trapika, Ni Putu Sriwidyani & I Gusti Kamasan Nyoman Arijana · Journal of Cancer and Tumor International · 2024

Aims: Hepatocellular carcinoma accounts for approximately 90% of all primary liver malignancies and poses a major global health challenge. The initiation of hepatocellular carcinoma (HCC) is marked by a progressive accumulation of molecular alterations, the origins of which remai...

Open access Research Article 10.9734/jcti/2024/v14i4269

In silico Toxicity and Pharmaceutical Properties to Get Candidates for Antitumor Drug

Dewa Ayu Made Adnyaswari, Agung Wiwiek Indrayani & I. Gusti Ayu Artini · Journal of Pharmaceutical Research International · 2024

Background: Drug metabolism is a crucial aspect of medical practice and pharmacology, involving the transformation of drugs by various bodily systems to create compounds that are more easily eliminated from the body. Sorafenib was reported as a useful adjuvant treatment in patien...

Open access Research Article 10.9734/jpri/2024/v36i27497