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Domaine T. Mwanangombo

Publications (8)

Facing COVID-19 Via Anti-Inflammatory Mechanism of Action: Molecular Docking and Pharmacokinetic Studies of Six Anti-Inflammatory Compounds Derived from Passiflora edulis

Aristote Matondo, Jason T. Kilembe, Domaine T. Mwanangombo, Beaudrique M. Nsimba, Dani T. Mawete, Benjamin Z. Gbolo, Gédéon N. Bongo, D. O. Opota, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda, Damien S. T. Tshibangu, Virima Mudogo & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2021

Aim: In the most severe case of the COVID-19, there is an excessive production of proinflammatory cytokines, being the main cause of mortality and morbidity. The present study aims at assessing the potential inhibitor effect of six phytochemicals with anti-inflammatory activity d...

Open access Research Article 10.9734/jocamr/2020/v12i330211

Aloe vera (L.) Burm. F. as a Potential Anti-COVID-19 Plant: A Mini-review of Its Antiviral Activity

Pius T. Mpiana, Koto-Te-Nyiwa Ngbolua, Damien S. T. Tshibangu, Jason T. Kilembe, Benjamin Z. Gbolo, Domaine T. Mwanangombo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo & Dorothée D. Tshilanda · European Journal of Medicinal Plants · 2020

Aims: A novel β-coronavirus (2019-nCoV) has become a pandemic affecting hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods which can help to curb this pandemic is urgent. This study aims to review the literatu...

Open access Research Article 10.9734/ejmp/2020/v31i830261

A Mini Review on the Phytochemistry, Toxicology and Antiviral Activity of Some Medically Interesting Zingiberaceae Species

Clément M. Mbadiko, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Aristote Matondo, Domaine T. Mwanangombo, Etienne M. Ngoyi, Gédéon N. Bongo, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2020

Background: Plants of the Zingiberaceae family namely Curcuma longa, Aframomum melegueta and Zingiber officinale are known for their many biological activities such as the antiviral activity. Aim: To provide an updated knowledge on the phytochemistry, toxicology and antiviral act...

Open access Research Article 10.9734/jocamr/2020/v9i430150

Review on Ethno-botany, Virucidal Activity, Phytochemistry and Toxicology of Solanum genus: Potential Bio-resources for the Therapeutic Management of Covid-19

Koto-Te-Nyiwa Ngbolua, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Etienne M. Ngoyi, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana · European Journal of Nutrition & Food Safety · 2020

Background and Aim: Condiment plants are not only a source of food, flavors or food additives but also antivirals. The aim of the present work consisted in compiling ethno-botanical, phytochemical, toxicological and biological activities literature data reported on some species o...

Open access Research Article 10.9734/ejnfs/2020/v12i730246

Possible Effect of Aromatic Plants and Essential Oils against COVID-19: Review of Their Antiviral Activity

Damien S. T. Tshibangu, Aristote Matondo, Emmanuel M. Lengbiye, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Clément M. Mbadiko, Shetonde O. Mihigo, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2020

Aim: Till now, no specific treatment is available for COVID-19. This work is carried out with the aim of verifying in the literature the antiviral properties of aromatic plants and essential oils that can justify their use against the causative agent of COVID-19, SARS-CoV-2. Meth...

Open access Research Article 10.9734/jocamr/2020/v11i130175

Antiviral Activity, Phytochemistry and Toxicology of Some Medically Interesting Allium Species: A Mini Review

Emmanuel M. Lengbiye, Clément M. Mbadiko, Clarisse M. Falanga, Aristote Matondo, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Shetonde O. Mihigo, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2020

Aims: COVID-19 pandemic affects hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods, which can help to curb this pandemic is urgent. This study aims to collect the information on the virucidal and toxicity prop...

Open access Research Article 10.9734/ijpr/2020/v5i430145

Ocimum Species as Potential Bioresources against COVID-19: A Review of Their Phytochemistry and Antiviral Activity

Dorothée D. Tshilanda, Etienne M. Ngoyi, Carlos N. Kabengele, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Clément M. Mbadiko, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Giresse N. Kasiama, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2020

Aim: The aim of this work was to review literature data reported on some species of the Ocimum genus regarding their phytochemistry and antiviral potential in order to show how Ocimum species might be used in the management of COVID-19. Methodology: Various databases like PubMed,...

Open access Research Article 10.9734/ijpr/2020/v5i430143

Oleanolic Acid, Ursolic Acid and Apigenin from Ocimum basilicum as Potential Inhibitors of the SARS-CoV-2 Main Protease: A Molecular Docking Study

Aristote Matondo, Jason T. Kilembe, Etienne M. Ngoyi, Carlos N. Kabengele, Giresse N. Kasiama, Emmanuel M. Lengbiye, Clément M. Mbadiko, Clément L. Inkoto, Gédéon N. Bongo, Benjamin Z. Gbolo, Clarisse M. Falanga, Domaine T. Mwanangombo, Daniel O. Opota, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2021

Aim: The present study aims at identifying potential inhibitors from a set of ten compounds from Ocimum basilicum against the SARS-CoV-2 main protease, the chymotrypsin-like protease (3CLpro). Materials and Methods: Computational studies by molecular docking (Autodock tool) were...

Open access Research Article 10.9734/ijpr/2021/v6i230156