Lawrence John AJutor, Edibokun Theresa Orobator, Blessing Ben- Anioke, Victor Chiedozie Ezeamii, Mayowa Josiah Badmus, Uchechi Ngozichukwu Obiefule, Vincent Barrah, Mary Oluwabunmi Oyebode & Josiah Stephen·Journal of Cancer and Tumor International·2025
BRCA1 and BRCA2 genes, located on separate chromosomes, encode crucial multifunctional proteins that are important for correcting errors in DNA replication and cell division. The two genes work in tandem at different stages in the DNA damage response and for DNA repair and could...
Open access
Research Article10.9734/jcti/2025/v15i2296
Habib Olaniran Kolawole, Edibokun Theresa Orobator, Blessing Imade, Victor Damilare Oladele, Ezema Izuchukwu Gerald, Kamsiyochukwu Anita Ezeani, Daniel Ebubechi Obasi, Adegbesan Abiodun Christopher, Peter Bemigho Adewoyin & Lawrence John AJutor·Journal of Cancer and Tumor International·2025
There has been an increase in the amount of studies focusing on the relevance of tumour microenvironment (TME) in metastasis of breast cancer. Cancer-associated fibroblasts (CAFs) is one of the most abundant cells found in the TME that play key roles in the metastasis of cancers...
Open access
Research Article10.9734/jcti/2025/v15i2288
Daniel Temiloluwa Oyedemi, Chigozie Doris Opara, Edibokun Theresa Orobator, Olabisi Promise Lawal, Ijeoma Linda Okwuowulu, Tolulope Catherine Ajayi & Oladimeji Samson Onifade·Journal of Advances in Medicine and Medical Research·2025
Gunshot trauma is an increasing global public health concern, resulting in significant morbidity and mortality. In this review, we evaluated the most recent literature on best practices for emergency gunshot trauma care, emphasizing novel techniques to improve patient outcomes. ...
Open access
Research Article10.9734/jammr/2025/v37i45799
Lawrence John AJutor, Olutayo Nathanael Farinde, Edibokun Theresa Orobator, Toluwanimi Janet Kolapo, Izuchukwu Gerald Ezema, Victor Damilare Oladele, Tobi David Farinde, Adedapo Olosunde, Peace Godwin Monday & Ayomide Babatunde Ishola·International Research Journal of Oncology·2025
Non-small cell lung cancer (NSCLC) is regarded as the most prevalent form of lung cancer, accounting for approximately 85% of all cases worldwide. This type of cancer is highly affected by the tumour microenvironment (TME), where exosomal communication is a major contributor. Thi...
Open access
Research Article10.9734/irjo/2025/v8i1173
Josiah Stephen, Ikechukwu Kanu, Nwamaka Nneka Onyedum, Edibokun Theresa Orobator, Catherine Rono, Ngwoke, Chinaza Faith, Victor Omeiza David, Wonderful Oluwatoyin Anosike & Lawrence John AJutor·Journal of Cancer and Tumor International·2025
HLA class I molecules are essential for presenting tumour antigens to cytotoxic T-cells, but their dysregulation in cancer enables immune evasion and limiting the efficacy of immunotherapies for cancer. The objective of this review is to explore the function of HLA class I change...
Open access
Research Article10.9734/jcti/2025/v15i3299