Effect of Polymorphisms in Drug Transporters on Cisplatin Efficacy and Nephrotoxicity in Paediatric Osteosarcoma
Samaa Ramadan, Ahmed Nabil, Hadeer Ghonim, Asmaa Salama, Enas EL Nadi & Rania M. Labib · Journal of Pharmaceutical Research International · 2022
Introduction: Osteosarcoma (OS) is the most common type of primary bone tumor in children and adolescents. Chemotherapeutic resistance to cisplatin represents such a significant barrier in the successful treatment of Osteosarcoma. The degree of nephrotoxicity and drug resistance...
Open access
Research Article
10.9734/jpri/2022/v34i28A36026