Sickle cell disease is a systemic vasculopathy in which intravascular haemolysis, endothelial activation, leukocyte and platelet recruitment, and coagulation activation operate as a single self-reinforcing process now commonly described as thromboinflammation. Most of the mechani...
Open access
Research Article10.9734/ibrr/2026/v17i4399
Automated haematology analysers have transformed the way clinicians detect, monitor, and manage infectious diseases, moving the complete blood count from a slow manual procedure into a rapid, multi-parameter diagnostic platform. This review examines the technological evolution of...
Open access
Research Article10.9734/ijr2h/2026/v9i2234
This case-control study investigated the effects of the AstraZeneca COVID-19 vaccine on coagulation parameters in a cohort of 102 individuals, revealing a significant increase in activated partial thromboplastin time (aPTT) among vaccinated individuals (34.233±0.653 seconds vs 28...
Open access
Research Article10.9734/ijr2h/2025/v8i1171
The COVID-19 pandemic has underscored the imperative of effective vaccination strategies, and the AstraZeneca COVID-19 vaccine has been extensively deployed globally, including in Nigeria. However, the haematological effects of this vaccine in the Nigerian population remain poorl...
Open access
Research Article10.9734/ijr2h/2025/v8i1170
Pregnancy is a physiological condition that is associated some changes in haematological and immunological parameters. This study evaluated the levels of some systemic inflammatory and haematological parameters in pregnant women in Port Harcourt, Nigeria. A total of 275 pregnant...