Ernest Nogma Sombie

Hepatoprotective Effects of Calotropis procera (Ait.) R. Br Root Bark Extracts against Diethylnitrosamine Induced Liver Injury in Rats

Ernest Nogma Sombie, Adama Hilou, Noufou Ouedraogo, Jotham Yhi-Pênê N’do, Dramane Pare, Tata Kadiatou Traoré, Geoffroy G. Ouédraogo & André Tibiri · European Journal of Medicinal Plants · 2021

Background: Diethylnitrosamine (DEN) is a hepatotoxin whose metabolic activation by liver cytochromes P450 is responsible for the necrosis, mutagenicity and carcinogenicity of liver cells. The purpose of this study was to evaluate the protective effects of Calotropis procera root...

Open access Research Article 10.9734/ejmp/2021/v32i1130426

In vivo Antifibrotic Potential of Extracts of Acanthospermum hispidum DC. Evaluated in Wistar Rats Using Diethylnitrosamine

Jotham Yhi-Pênê N’do, Adama Hilou, Dramane Pare, Ernest Nogma Sombie, Samson Guenne & André Tibiri · International Journal of TROPICAL DISEASE & Health · 2019

Aims: Liver fibrosis is a chronic disease of the liver. This disease is a stage of passage to liver cancer. The objective of this work was to evaluate the ability of the ethanolic extract of Acanthospermum hispidum to block the progression of hepatic fibrosis induced in rats usin...

Open access Research Article 10.9734/ijtdh/2019/v36i130135

Protective Effect of Acanthospermum hispidum DC (Asteraceae) Extracts against Diethylnitrosamine Induced Hepatocellular Damage

Jotham Yhi-Pênê N’do, Adama Hilou, Dramane Pare, Ernest Nogma Sombie, Tata Kadiatou Traoré, Noufou Ouedraogo, André Tibiri & Latifou Lagnika · Journal of Complementary and Alternative Medical Research · 2019

Aims: Liver diseases are a major public health concern in the world. About 120 million cases of infectious HBV (the half of the world cases) are registered in sub-Saharan Africa. Burkina Faso is a country with a high endemicity of viral hepatitis. These diseases cause serious dam...

Open access Research Article 10.9734/JOCAMR/2018/44474