Sodium Butyrate as Adjuvant Therapy with Mycophenolate Mofetil for Amelioration of Skin Fibrosis in Bleomycin-induced Scleroderma in Mice via Immunomodulatory, Antioxidant, Antiapoptotic and Antifibrotic Mechanisms
Qamar Othman, Maaly A. Abdelmaaboud, Amany A. Abdin & Fleur Fathi · Journal of Advances in Medicine and Medical Research · 2022
Background: Scleroderma is an autoimmune, multi-organ disease; its clinical hallmark is cutaneous and systemic fibrosis. Up to date, there is no definite cure. Aim of the Study: The aim of this study was to investigate the potential effects of sodium butyrate (NaB), and mycopheno...