Fortune Itoje Ebiala, Jumoke Ologun, John Kelenna Iregbu, Ogochi Blessing Chukwuneke, Aliaa Mohammed Mahmoud Soliman, Ayo Ebunolorun Ibukunoluwa, Rasheedat A. Busari MD, Oluwatobiloba Kehinde Adedokun & Lawrence John AJutor·Journal of Cancer and Tumor International·2025
Background: Oncogene addiction occurs in most tumour cells it is a phenomenon capable of driving colorectal cancer (CRC) growth, where tumour cells rely on genes like KRAS, BRAF, or MYC to survive. This has been so far seen as an exploitable target for precision therapies. Aim: T...
Open access
Research Article10.9734/jcti/2025/v15i3316
Fortune Itoje Ebiala, Cecilia Chika Unegbu, Precious Oluwamosope OKUNOLA, Ogochi Blessing Chukwuneke, Ololade Funke Olaitan, Ndubisi Ubaka Edebeatu & Damilola Ayodele Ojo·Journal of Cancer and Tumor International·2025
Beyond the human genetic codes, epigenetics also plays a key role in regulating how genes are expressed. While mutations or genes are known to be major causes of cancer, Epigenetic alterations, including DNA methylation, histone modifications, and non-coding RNAs, play critical r...
Open access
Research Article10.9734/jcti/2025/v15i3317
Esther Uyoyooghene Olokede, Kingsley Ugonna Ugoagwu, Olusegun Timothy God-Giveth, Motunrayo Victoria Adigun, Fortune Itoje Ebiala & Salifu Faisal·International Research Journal of Oncology·2026
Spatial transcriptomics and related spatially resolved profiling technologies have transformed the characterization of tumor microenvironment architecture, revealing spatial patterns of cellular organization that are tightly linked to cancer behavior. However, despite their biolo...
Open access
Research Article10.9734/irjo/2026/v9i1198