Isoflurane and Ketamine/Xylazine Anesthesia do not Influence the Neuroprotective Effects of Simvastatin in a Model of Permanent Cerebral Ischemic Injury in C57BL/6J Mice
Maria Linou, Era Taoufik, Georgios Kazakos, fstathios Boviatsis, Lila Papadimitriou & Ismene A. Dontas · Journal of Advances in Medicine and Medical Research · 2015
Laboratory mice with Middle Cerebral Artery Occlusion (MCAO) represent the main animal models for ischemic stroke research. Appropriate anesthetic protocols are essential, as anesthetic agents might affect the central nervous system (CNS) and therefore interfere with the outcome...
Open access
Research Article
10.9734/BJMMR/2015/19288