Gladys Dotto

Plasmatic Biochemical Variables Associated with Polymorphisms in the Endothelin-1 and Endothelin-1 Receptor a Genes in Hypertensive Patients: Pilot Study

Oscar Lassen, Jimena Herrera, Gladys Dotto, Silvia Ojeda, Alicia Garutti, Patricia Bertolotto, Sandra Tabares & Adela Sembaj · Journal of Advances in Medicine and Medical Research · 2015

Aims: Endothelin-1 (ET-1) is a potent vasoconstrictive peptide, and its activity is mediated by the type A receptor (EDNRA). This action may play a significant role in the etiology of hypertension. There are different works that shows an association between certain polymorphisms...