Nonivamide (N-(4-hydroxy-3-methoxybenzyl) nonanamide), also known as pelargonic acid vanillylamide (PAVA), is an industrially important synthetic capsaicinoid with potent transient receptor potential vanilloid subtype-1 (TRPV1) agonistic activity and extensive applications in pha...
Open access
Research Article10.9734/jsrr/2026/v32i94512
Astaxanthin, a high-value xanthophyll carotenoid with potent antioxidant activity, was efficiently extracted from the microalga Haematococcus pluvialis using an integrated green extraction strategy combining pulsed electric field (PEF)-assisted cell disruption and supercritical C...
Open access
Research Article10.9734/jsrr/2026/v32i54168
A systematic Intrinsic network pharmacology methodology was employed to determine the multi-target therapeutic activity of Rosmarinic acid in endometritis. Prediction of target proteins was performed using Swiss Target Prediction and PharmMapper, followed by protein–protein inter...
Open access
Research Article10.9734/jpri/2025/v37i97748
Non-alcoholic fatty liver disease (NAFLD) is a significant world health burden, occurring in more than 25% of the adult population and advancing to steatohepatitis, fibrosis, and eventually cirrhosis or hepatocellular carcinoma. Although it is increasingly prevalent, there are li...
Open access
Research Article10.9734/jpri/2025/v37i77721
Contemporary chronic diseases, including pervasive Vitamin D3 and B12 deficiencies, are increasingly considered failures of intricate metabolic and regulatory networks—rather than isolated biochemical imbalance. Deficiencies interrupt integrated processes such as redox signaling,...
Open access
Research Article10.9734/acri/2025/v25i61281
This study introduces a novel technique that uses a solvent mixture of 60% water and 40% ethanol to extract caffeine, theophylline, and polyphenols from green tea leaves (Camellia sinensis) all at once. On a dry basis, the Folin-Ciocalteu Reagent Method (ISO 14502-1) estimated th...
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Research Article10.9734/sarjnp/2024/v7i3172
The recent resurgence of the Monkeypox Virus (MPXV) has prompted increased efforts to discover effective antiviral treatments. This study utilized an in silico docking approach with CB Dock2 to assess both natural compounds and repurposed antiviral medications. We concentrated on...
Open access
Research Article10.9734/jpri/2024/v36i117599
This study explores the extraction and purification of carnosic acid, a potent antioxidant found in rosemary (Rosmarinus officinalis), using a green and sustainable method involving supercritical CO₂. The extraction was conducted at 45°C and 350 bar, with three cycles lasting 45...
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Research Article10.9734/CSJI/2024/v33i6920
The significance of this research extends beyond the mere extraction and purification of allicin, encompassing its potential applications across diverse industries. Allicin exhibits a plethora of biological activities, including antimicrobial, antifungal, antiviral, and antiproto...
Open access
Research Article10.9734/ijbcrr/2024/v33i6887
Squalene, a highly valuable compound abundant in various natural sources, shows great potential in pharmaceutical, cosmetic, and nutraceutical applications. This research article outlines a comprehensive methodology for extracting and purifying squalene from virgin olive oil, a r...
Open access
Research Article10.9734/ejmp/2024/v35i31191
Berberis aristata a Himalayan woody spiny shrub with yellow flowers and red berries commonly called as Daruharidra in Sanskrit and locally in Nepal is called as Chutro or Chitra. The root and stem are the two parts widely used in traditional medicines of India and China. Berberin...
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Research Article10.9734/ejmp/2021/v32i1230434
Ergot of Rye is a plant disease caused by the fungus Claviceps purpurea which infects the grains of cereals and grasses but it is being used for ages for its medicinal properties. All the naturally obtained ergot alkaloids contain tetracyclic ergoline ring system, which makes the...
Open access
Research Article10.9734/EJMP/2016/25975