Full Blood Count Platelet Parameters in Sickle Cell Disease: A Systematic Review of Thrombocytosis, Thrombocytopenia, and Clinical Implications
Jacques Forwah Ndeh, Edung Emen Samuel, Ofonime Benjamin Essien, Bassey Okon Bassey, Mansurat Oluwasshola Alabi, Ihuoma Fidelia Onunaku, Joy Oyemwen Aikpitanyi, Diderot Tiemen Charles, Ewa Anthony Obi, Idiege Idiege Omang, Edomaruse Maxwell Joseph, Alu Owere Emmanuel, Prince-Nnabugwu Ruth Amarachukwu, Adegboyega Akintola, Asuquo Ukemeobong Michael, Maduka Ekene Ekezie, Gbeminiyi Ebenezer Adekanmbi, Ike-Ogbonna Ginikachi Valerie, Agbayewa Ademola, Chioma Kenis Onyejekwe, Oluwatobiloba Akinwale, Egwowa M. Elo-Oghene, Bushirat Mulero, Sally Tsagli, Abdullah Damilare Shonola, Oyibo Basil Eze, Princess Adebanwi, Akaba Kingsley Onoridea, Nnaji Chimuanya Joseph, Ushie Godwin Abua, Immaculate Ihuoma Ekeagba, Tams Isaac Tamunobelema & Abeshi Sylvester Etenikang · International Journal of Research and Reports in Hematology · 2026
Background: Sickle cell disease (SCD) is characterized by chronic hemolysis, endothelial dysfunction, and systemic inflammation, each of which disrupts platelet homeostasis. The full blood count (FBC), the most universally available hematological test, remains underutilized in ro...