Ilva F. Souza

Morphology of Adherent Cells of the Line Vero Cultivated in a Three-Dimensional Environment inside a Microfluidic Device Differs from their Morphology when Cultivated in Monolayers

João Paulo J. Vieira, Ilva F. Souza, Marcelo B. Pedras, Danilo B. Oliveira, Libardo A. González-Torres & Bethânia A. Avelar-Freitas · Journal of Advances in Medicine and Medical Research · 2024

Traditional in vitro culture models have significant limitations in mimicking important physiological interactions, such as cell-cell interactions, cell-extracellular matrix interactions, and the three-dimensional morphology of cells. In contrast, 3D culture models have the abili...