Background: Arthritis and fibromyalgia are chronic inflammatory conditions that cause significant pain and discomfort in affected individuals. Current treatments, such as nonsteroidal anti-inflammatory drugs (NSAIDs), are associated with adverse effects and do not always provide...
Open access
Research Article10.9734/jammr/2023/v35i155083
The opioid overdose crisis has escalated into an international public health emergency, with mortality rates continuing to rise, a trend that was further intensified during the COVID-19 pandemic. Individuals with mental health conditions such as anxiety, depression, and thought d...
Open access
Research Article10.9734/jammr/2025/v37i45778
This systematic review and meta-analysis compared the efficacy of lifestyle interventions versus pharmacotherapy for managing Non-Alcoholic Fatty Liver Disease (NAFLD) across 12 studies. Pharmacological agents, particularly pioglitazone and liraglutide, demonstrated greater reduc...
Open access
Research Article10.9734/jammr/2025/v37i15712
Cardiac failure (HF) is a multifaceted clinical center described by the incapacity of a heart to sufficiently pump blood leading to inefficient perfusion of tissues. It has two main categories that are represented by ejection fraction: Heart Failure with Reduced Ejection Fraction...
Open access
Research Article10.9734/jammr/2024/v36i85551
Background: The one of most common and severe complications is diabetic kidney disease, which leads to in the long term. However, there are many recent developments in medical therapy, especially when we use inhibitors SGLT2, which always gives us the best outcome in improving pa...
Open access
Research Article10.9734/jammr/2024/v36i55443
NSAIDs, or nonsteroidal anti-inflammatory medications, are popular and efficient analgesis and frequent mainstay treatements for inflammatory disorders. However, their cardiovascular safety is questionable. The aims of the current study were: (1) to evaluate the comparative cardi...
Open access
Research Article10.9734/jammr/2024/v36i55427
Introduction: Type 2 diabetes mellitus (T2DM) is a chronic condition where obesity plays a key role. Metformin is commonly used to manage T2DM, with benefits in both glycemic control and weight management. This systematic review and meta-analysis update the evidence on metformin’...
Open access
Research Article10.9734/jammr/2024/v36i95571
Heart failure is one of the most frequent and severe diseases today, which is characterized by a high mortality rate and a high rate of sudden cardiac death, primarily because of ventricular arrhythmias. ICD is one of the most useful and widely used device to manage high-risk HF...
Open access
Research Article10.9734/jammr/2024/v36i115615
Ahtisham UL Haq, Abida Batool, Keerthi S. Chitneni, Maheshwar Dumpala, Ashraf Ullah, Mudit Moondra, Jamil A. Dayo, Mohd Diya Masmoum, Darshakkumar J. Senjaliya & Imdad Ullah·Journal of Advances in Medicine and Medical Research·2024
Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder causing chronic abdominal pain, bloating, and altered bowel habits, with inadequate treatments integrating into daily patient care. The low FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, a...
Open access
Research Article10.9734/jammr/2024/v36i95570
Arhum Mahmood, Marium Abid, Rubela Ray, Azam Sikander, Uzma Nureen, Syed Muhammad Rehman Shah, Raneem Masmoum, Shaf A. Altaf, Sumaiyya Mohiuddin, Binish Essani & Imdad Ullah·Journal of Advances in Medicine and Medical Research·2024
Cardiac dysfunction or heart failure (HF) continues to be a leading cause of morbidity and mortality globally with more than 64 million affected people. Despite advancements in pharmacotherapy, patients with heart failure (HF) continue to face significant risks of mortality and h...
Open access
Research Article10.9734/jammr/2024/v36i105599
Raheel Chaudhry, Masooma Afridi, Arhum Mahmood, Shahroz M. Khan, Hadeel Al Kayed, Syeda I. Tahera, Ayesha Saleem, Muhammad Sajawal, Mohd.Diya Masmoum, Farhana Nazmin & Imdad Ullah·Journal of Advances in Medicine and Medical Research·2024
There remains a debate on the effects of alcohol use on cardiovascular health. This systematic review and meta-analysis examined the relationship between this link and blood pressure, lipid profiles, and the frequency of cardiovascular events to shed light on it. A comprehensive...
Open access
Research Article10.9734/jammr/2024/v36i75497
Shahroz M. Khan, Farhana Nazmin, Rubela Ray, Rauann Hachem, Briannah Wade, Manal A. Bhinder, Muhammad B. Chaudhry, Marya Syed, Ayesha Khan, Eman Fatima & Imdad Ullah·Journal of Advances in Medicine and Medical Research·2024
Chronic hepatitis C with cirrhosis is treated with direct-acting antibiotics (DAAs). The aim of this study was to investigate the effect of direct-acting antibodies in the treatment of hepatitis C in cirrhosis. It also examines the proportion of drug-related problems, side effect...
Open access
Research Article10.9734/jammr/2024/v36i65469