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Israel O. Efejene

Publications (7)

Immunohistochemistry and Histology Evaluation of Neurodevelopmental and Neurocognitive Changes in the Offspring of Depressed Mice Administered Paroxetine Prenatally

Israel O. Efejene, Benneth Ben-Azu, Anthony T. Eduviere, Osuvwe C. Orororo, Meashack O. Ijomone, Mega O. Oyovwi, Michael E. Aisuodionoe & Abdulwasiu A. Busari · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Depression, a prevalent biopsychiatry disability leading to dysfunction behavioural abilities due to its symptomatic expression, is much more severe in gestational period affected both maternal and child’s health. Paroxetine, a selective serotonin reuptake inhibitors (SSRI) is us...

Open access Research Article 10.9734/ajrimps/2026/v15i1363

Evaluation of Pattern of Antibiotics Utilization among Fish Farmers and Detection of Tetracycline, Oxytetracycline and Ceftriaxone Residue in Fish Samples in Lagos, Nigeria

Israel O. Efejene, Paulette O. Ogbebor, Paulyn O. Ogbebor, Osuvwe C. Ororoxro, Abdulwasiu A. Busari, Sunday O. Olayemi, Ibrahim A. Oreagba, Favour O. Igari, Michael E. Aisuodionoe, Esthinsheen Osirim & Egoamaka O. Egbune · Asian Journal of Fisheries and Aquatic Research · 2025

Aquaculture uses antibiotics to treat or prevent bacterial infections, however, negative consequences including the emergence and dissemination of resistant pathogenic bacteria are quite concerning. In addition, the persistence of antibiotic residues (ARs) in fish is fast becomin...

Open access Research Article 10.9734/ajfar/2025/v27i7958

Protective Effects of Telfairia occidentalis and Carica papaya Leaf Extracts on Hematological and Lipid Alterations in Phenylhydrazine-Induced Anemia in Rats

Osuvwe C. Ororoxro, Israel O. Efejene, Eromosele M. Aisuodionoe, Oghenevwegba P. Ishokare, Emmanuel O. Ogbotor & Precious Ogbodu · Asian Hematology Research Journal · 2026

Anaemia is a major global health challenge and is commonly associated with oxidative stress, haemolysis and metabolic disturbances, including dyslipidaemia. Phenylhydrazine (PHZ)-induced haemolytic anaemia is a widely used experimental model characterised by erythrocyte destructi...

Open access Research Article 10.9734/ahrj/2026/v9i4277

Evaluation of Anti-Inflammatory and Analgesic Effects of Allophylus spicatus Leaf Extract in Mice

Osunu M. Idenyi, Osuvwe C. Orororo, Israel O. Efejene, Michael E. Aisuodionoe & Uboho F. Umoren · Journal of Complementary and Alternative Medical Research · 2024

This study examined the analgesic and anti-inflammatory activity of an ethanolic extract of Allophylus spicatus leaves in albino mice, taking into account the socioeconomic impacts of pain and inflammation as well as the need to search for effective antipain and anti-inflammatory...

Open access Research Article 10.9734/jocamr/2024/v25i9571

Assessment of Cardiovascular Function in Periodontitis and Diabetes Mellitus Induced Rats Treated with Black Seed (Nigella sativa) Oil

Abdulwasiu. A. Busari, Chidinma C. Obadiah, Osuvwe C. Orororo, Israel O. Efejene, Michael E. Aisuodionoe, Esthinsheen Osirim, Samantha DeLoache, Collins I. Ebu, Abdullahi A. Adejare & Kabir Badmos · Asian Journal of Cardiology Research · 2024

Diabetic periodontitis and diabetes worsen cardiovascular disease, which is a major cause of morbidity and death globally. Although Nigella sativa (NS) oil has anti-inflammatory, antioxidant, and hypoglycemic qualities, little is known about how well it can treat periodontitis an...

Open access Research Article 10.9734/ajcr/2024/v7i1224

Co-administration of Vitamin E and Quercetin Ameliorates Sodium Fluoride-induced Toxicities in Wistar Rats

Gabriel O. Ibobo, Divine A. Onobrudu, Osuvwe C. Orororo, Othuke B. Odeghe & Israel O. Efejene · Asian Journal of Research in Biochemistry · 2025

High dosages of fluoride have damaging effects on humans and animals. This study examined the beneficial role of co-administration of quercetin and vitamin E on sodium fluoride (NaF)-induced toxicities in Wistar rats because there are few documented reports on the synergistic eff...

Open access Research Article 10.9734/ajrb/2025/v15i3382

You Are What You Eat: Preventive Roles of Antioxidant Phytochemicals on Age-related Eye Diseases

John E. Moyegbone, Eghonghon E. Onoikhua, Favour A. Fregene, Kingsley N. Jacob, Israel O. Efejene, Edmond I. Anowa, Omatseye A. Akuirene, Emmanuel E. Agege, Joseph O. Odoko & Ezekiel U. Nwose · European Journal of Medicinal Plants · 2023

Aim: What we eat plays a vital role in human health with no exception to the eye which results to either good or poor vision. This review aimed at determining how what we eat affect age-related eye diseases and the role of antioxidants in phytochemical compound in preventing age-...

Open access Research Article 10.9734/ejmp/2023/v34i101162