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Jayakar Thomas

Publications (10)

Spironolactone in Dermatology: A Mini Review

Jayakar Thomas, S. Soundarya & S. Vaishnavi · Journal of Pharmaceutical Research International · 2021

Spironolactone is a drug, similar in structure to aldosterone and acts as an aldosterone receptor antagonist with an anti-androgenic effect. This drug has proven to be useful in several dermatological entities, however its use has not been well explored. Its use in diseases such...

Open access Research Article 10.9734/jpri/2021/v33i60B34861

Systemic Sclerosis: A Case Report and Review of Current Advances in Treatment

Aishwarya Shankar & Jayakar Thomas · Journal of Pharmaceutical Research International · 2022

Systemic sclerosis (SSc) is a chronic multisystem disease characterized by excess deposition of connective tissue in skin and internal organs, associated with microvasculature changes and immunologic abnormalities. We hereby report a case of scleroderma in a 52 year old female wi...

Open access Research Article 10.9734/jpri/2022/v34i597265

A Case Report of ChAdOx1 nCoV- 19 Corona Virus Recombinant Vaccine Related Granuloma Annulare

S. Swetha Shri & Jayakar Thomas · Journal of Pharmaceutical Research International · 2021

Background: Granuloma annulare (GA) is a benign, self-limiting inflammatory skin condition of unknown origin that may occur following multiple etiological triggers. GA incited secondary to vaccinations has been rarely reported in the medical literature. The COVID-19 pandemic has...

Open access Research Article 10.9734/jpri/2021/v33i51B33533

Histopathological Correlation in Different Types of Leprosy in a Tertiary Health Care Centre

M. Ravali & Jayakar Thomas · Journal of Pharmaceutical Research International · 2021

Hansen’s disease or Leprosy, is a chronic infectious disease that is contagious and has a slow evolution. It affects mainly skin and schwann cells in the peripheral nerves and causes peripheral neuropathy which contributes to the permanent functional impairments [1]. It is caused...

Open access Research Article 10.9734/jpri/2021/v33i47A33022

A Observational Study on Hypopigmented \ Depigmented Macules in Geriatric Population Attending Dermatology OPD in a Tertiary Care Centre

B. Shea Sharma & Jayakar Thomas · Journal of Pharmaceutical Research International · 2021

This article lays out the common hypopigmented \depigmented lesions in geriatric population encountered in dermatology OPD in a tertiary care centre in India. Hypopigmented/depigmented lesions is commonly encountered in a dermatology OPD on a day to day basis. This study is an ob...

Open access Research Article 10.9734/jpri/2021/v33i45A32733

Dermatophytosis in a Suburban Hospital-A Study on Distribution and Clinical Types According to Age and Sex

Aishwarya Shankar & Jayakar Thomas · Journal of Pharmaceutical Research International · 2021

Aim and Objectives: Dermatophytosis is a fungal infection of the outermost layer of skin and its appendages such as hair, nails and scalp. The present study was undertaken with a view to find out the clinical pattern of dermatophytic infections in our hospital. Materials and Meth...

Open access Research Article 10.9734/jpri/2021/v33i45A32722

Frequently Thickened Nerve in Hansen’s Disease

P. Vignesh Shivaraman & Jayakar Thomas · Journal of Pharmaceutical Research International · 2021

Background: Leprosy by definition is a chronic granulomatous infection of the skin and superficial nerves in the skin caused by Mycobacterium leprae and Mycobacterium lepromatosis. [1] It most commonly involves the nose, eyes, throat, and sometimes the testicles. The bacilli are...

Open access Research Article 10.9734/jpri/2021/v33i44B32686

Analytical Pattern in Dermatoglyphics

S. R. Sruthy & Jayakar Thomas · Journal of Pharmaceutical Research International · 2020

Aim: The aim was to study the analytical pattern in dermatoglyphics. Materials and Methods: The study was conducted in Skin Opd, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India. A total of 100 participants with different hand dermatitis pattern were included...

Open access Research Article 10.9734/jpri/2020/v32i1330576

A Comparative Study of Topical 3% Tranexamic Acid and 35% Glycolic Acid in Melasma and Review of Literature

S. Soundarya, N. Devanand, Vaishnavi Sabapathi & Jayakar Thomas · Journal of Pharmaceutical Research International · 2021

Aim: To compare the efficacy and safety of topical 3% tranexamic acid gel vs 35% glycolic acid peel in the treatment of melasma over face. Materials and Methods: This is an open labelled, Randomised Controlled Trial(RCT) conducted on 60 patients. Patients were randomly divided eq...

Open access Research Article 10.9734/jpri/2021/v33i43A32483