Joyce Nyirongo

Astemizole-Methylene Blue Combination Therapy Reduces Monotherapy Adverse Effects in Balb/C Mice

Joyce Nyirongo, Faith Onditi, Jemimah Simbauni, Lucy Kamau, Victor Mwangi, Esther Kagasi & Hastings Ozwara · Journal of Pharmaceutical Research International · 2022

Aims: To determine the toxicity of astemizole-methylene blue combination therapy as effective candidates for therapeutic repurposing against malaria. Study Design: Randomized block study design. Place and Duration of Study: Department of Tropical and Infectious Diseases, Institut...

Open access Research Article 10.9734/jpri/2022/v34i53A7226

Drug Recovery: Effect of Astemizole - Methylene Blue Combination Therapy against Plasmodium Strains in vitro

Joyce Nyirongo, Lucy Kamau, Jemimah Simbauni, Victor Mwangi, Esther Kagasi, Faith Onditi & Hastings Ozwara · South Asian Journal of Parasitology · 2020

Plasmodium species are protozoa from the Apicomplexa phylum which cause malaria. In the tropics and sub-tropics, approximately 3.3 billion people are threatened by this disease. Artemisinin Combination Therapy, has been reported to have a possible emergence of resistance. Therefo...

Open access Research Article