Katherina Walz

Characterization of a Trpc6 Transgenic Mouse Associated with Early Onset FSGS

Cesar P. Canales, Paola Krall, Pamela Kairath, Irene C. Perez, Miryam A. Fragoso, Paulina Carmona-Mora, Phillip Ruiz, Jochen Reiser, Juan I. Young & Katherina Walz · Journal of Advances in Medicine and Medical Research · 2014

Rationale: Mutations in Transient Receptor Potential Channel 6 (TRPC6) gene are associated with autosomal dominant focal and segmental glomerulosclerosis (FSGS). The majority of the identified mutations affect the ion channel function. Since calcium channels are promising candida...