Kéita Mélalie

Identification of Novel Polyketide Synthase 13 of Mycobacterium Tuberculosis Inhibitors: A Modelling Approach Using the Pharmacophore Method -Based Virtual Screening

Djako Akassa Marius Bernard, Niaré Adama, Fofana Issouf, Moussé Logbo Mathias, Kéita Mélalie & Megnassan Eugène · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. It remains a major public health problem worldwide. In 2022, 10.6 million people contracted tuberculosis and 1.3 million died from it.  This manuscript presents our work, the aim of which is to find new i...

Open access Research Article 10.9734/jamps/2025/v27i6784

Molecular Modeling and Virtual Screening: Application to Computer-Aided Design of Anticancer Inhibitors of Human Dihydroorotate Dehydrogenase

N’doman Gossan Roméo, Bibila Mayaya Bisseyou Yvon, Djako Akassa Marius Bernard, Niaré Adama, Akori Esmel Elvice, Kéita Mélalie & Megnassan Eugène · Journal of Pharmaceutical Research International · 2025

Abnormal and uncontrolled cell growth leading to dysfunction of cellular metabolism causes a serious disease called cancer. In 2022, 20 million people had cancer and 9.7 million died. Cancer is a real health problem given the number of deaths caused by this disease. This article...

Open access Research Article 10.9734/jpri/2025/v37i87734