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Linus O. Agwu

Publications (6)

Ameliorative Effects of Ethanol Leaf Extract of Annona muricata on the Renal Function of N-Nitroso-N-methylurea (NMU)- Induced Prostate Cancer in Albino Rats

Onyinyechi Chijioke Njoku, Linus O. Agwu, Chimdi Ezichi Esonu, Chibuike Valentine Edom, Moshood A. Haruna, Winifred N. Nsofor, Thaddeus O. Ukwueze, Nnenna C. Osuji-Kalu, Blessing A. Mba, Chinweuba G. Nwaekpe & Tasi’u M. Uba · International Research Journal of Gastroenterology and Hepatology · 2025

Background: Kidney related disorders arising from several diseases has been a challenge in recent times. The aim of this study was to evaluate the effect of A. muricata ethanol leaf extract on renal function parameters of NMU-induced prostate cancer in albino rats. Materials and...

Open access Research Article 10.9734/irjgh/2025/v8i1127

Hepatoprotective Potential of Methanol Extract of Allium cepa against Paracetamol-induced Hepatotoxicity in Wistar Rats

Rosemary C. Njoku, Aloysius C. Ene, Cosmas O. Ujowundu, Favour N. Ujowundu, Viola A. Onwuliri, Blessing A. Mba, Linus O. Agwu & Kingsley U. Obasi · International Journal of Biochemistry Research & Review · 2025

Paracetamol overdose is a primary cause of drug-induced hepatotoxicity, mediated through oxidative stress pathways. This study determined the protective efficacy of Allium cepa methanolic extract against paracetamol-induced liver damage. Methanol extract yield of Allium cepa and...

Open access Research Article 10.9734/ijbcrr/2025/v34i51060

Phytochemical Profiling and Combinatorial-Optimization of Zingiber officinale, Allium sativum and Curcuma longa Extracts for In-vitro \(Fe^{2+}\)-Chelation as Potential Heavy-Metal Detoxifiers

Joshua C. Ezema, Opeyemi D. Omoleye, Joshua O. Kanwanye, Sunday C. Chukwudoruo, Kizito M.E. Iheanacho, Cosmas O. Ujowundu, Favour N. Ujowundu, Linus O. Agwu, Viola A. Onwuliri & Kingsley O. Obasi · Asian Journal of Research in Biochemistry · 2025

This research investigated the bioactive compounds of Zingiber officinale (ginger), Allium sativum (garlic) and Curcuma longa (turmeric) and the combinatorial capacity of the extracts to chelate ferrous (Fe2+) ions. Phytochemicals were determined using gas chromatography-flame io...

Open access Research Article 10.9734/ajrb/2025/v15i6443

Assessment of Cardiometabolic Risks Associated with Administration Graded Doses of Methanol Root Extract of Newbouldia laevis in Rats

Chimezie J. Obika, Aloysius C. Ene, Cosmas O. Ujowundu, Favour N. Ujowundu, Viola A. Onwuliri, Kingsley U. Obasi, Blessing A. Mba & Linus O. Agwu · Asian Journal of Medical Principles and Clinical Practice · 2025

Herbal therapies with antimalarial activities are increasingly studied not just for efficacy but also for safety. Methanol root extract of Newbouldia laevis has shown antimalarial potential in mice, however, the lipid-modulating effects remain unclear. This study investigated the...

Open access Research Article 10.9734/ajmpcp/2025/v8i2342

Evaluation of Combined Effect of Ocimum gratissimum and Ageratum conyzoides Leaf Powder as a Sustainable Bioinsecticide against Cowpea Weevil

Victor C. Ihebom, Cosmas O. Ujowundu, Callistus I. Iheme, Favour N, Ujowundu, Christopher O. Echereobia, Ngozi U. Nwogwugwu, Adaeze A. Nwakaudu, Margaret N. Ibe, Raymond C. Ibeh, Linus O. Agwu, Kingsley U. Obasi & Emmanuel C. Okwara · Asian Journal of Research in Biochemistry · 2025

This study was conceived to improve the preservation of cowpea grains by eliminating the destruction of cowpea grains by cowpea weevils (Callosohruchus maculates) and to eliminate the detrimental effect of synthetic pesticide on the environment. This study evaluated the proximate...

Open access Research Article 10.9734/ajrb/2025/v15i6442

In-vitro Antioxidant and Metal Chelation Properties of Ginger, Garlic and Turmeric Extracts: A Nutraceutical Approach to Reducing Oxidative and Metal-Induced Stress

Joshua C. Ezema, Blessing T. Nwafor, John E. Udensi, Blessing C. Chiagorom, Chisom I. Obasi, Christiana I. Daniel, Winnie D. Olu, Ruth A. Francis, Vivian O. Ibekwe, Sunday C. Chukwudoruo, Kizito M.E. Iheanacho, Cosmas O. Ujowundu, Favour N. Ujowundu, Linus O. Agwu & Viola A. Onwuliri. · Asian Journal of Medical Principles and Clinical Practice · 2025

Heavy metal exposure and toxicity pose significant risks to human health, resulting in endocrine dysruption, oxidative stress, neurodegeneration and breakdown of the immune system. This study investigated the in vitro antioxidant and metal chelating capacity of combined extracts...

Open access Research Article 10.9734/ajmpcp/2025/v8i2343