Mahrukh Malik

Down Regulation in Glutathione S-Transferase Stimulate Oxidative Stress and Genetic Susceptibility of Human Breast Cancer

Asia Adil, Mahrukh Malik, Javeria Arshad Malik, Sara Nazir & Irum Sabir Ali · Journal of Pharmaceutical Research International · 2022

Glutathione S-Transferase is an enzyme that catalyzed the formation of thio-ether conjugates between the endogenous tripeptide glutathione and xenobiotic compounds. Imbalance of glutathione level is observed in a variety of disease including breast cancer. In the present study we...

Open access Research Article 10.9734/jpri/2022/v34i20B35827

Study of Antiemetic Potential of Ruta graveolens Extracts by Copper Sulphate and Brassica campestris Induced Emesis in Chicks

Sara Nazir, Javeria Arshad Malik, Mahrukh Malik, Muhammad Usman Gondal, Muhammad Shoaib Muhammad Shoaib Akhtar & Alia Erum · Journal of Pharmaceutical Research International · 2021

The antiemetic effect of aqueous and methanolic extracts of R. graveolens in young chicks was investigated. In addition, the phytochemical screening of the test plant and its acute toxicity studies were also conducted. Different doses of the extracts were tested for their antieme...

Open access Research Article 10.9734/jpri/2021/v33i32A31715