We propose a new stepwise confidence set procedure for toxicity study based on ratio of mean difference. Statistical approaches for evaluating toxicity studies that properly control familywise error rate (FWER) for difference of means between treatments and a control already exis...
Open access
Research Article10.9734/arjom/2021/v17i1130341
We propose a stepwise confidence procedure for identifying minimum effective dose (MED) without multiplicity adjustment.Stepwise procedures strongly control the familywise error rate (FWER) which is a critical requirement for statistical methodologies in identification of MED. Th...
Open access
Research Article10.9734/arjom/2021/v17i430292
In this article we consider identification of maximum safe dose (MSD) in a dose response study for distribution-free endpoints. Where the maximum safe dose is the highest dose level that does not exceed the median toxicity of the zero dose by a predetermined margin. A nonparametr...
Open access
Research Article10.9734/ARJOM/2017/36377