Michael Sakha

Immune Editing of Stem Cell Fate: Implications for Cancer Initiation and Therapy Resistance

Dickens Agie & Michael Sakha · Journal of Cancer and Tumor International · 2026

Stem cell fate has traditionally been viewed as a product of intrinsic transcriptional programs and epigenetic regulation operating within specialized tissue niches. However, growing evidence suggests that immune-derived signals constitute a powerful and underappreciated force sh...

Open access Research Article 10.9734/jcti/2026/v16i2348

Optimization of Cellulase Production by Daldinia concentrica through Variation of Incubation Time and Lignocellulosic Substrate under Solid-State Fermentation

Dickens Agie, George Omwenga, Arika W. Makori, Patroba Ojola & Michael Sakha · Asian Journal of Biotechnology and Bioresource Technology · 2025

A significant portion of agricultural and industrial by-products, such as sugarcane bagasse, rice husks, and eucalyptus sawdust, are underutilised despite their potential as abundant sources of cellulose. Fungal species are excellent producers of cellulases that hydrolyze cellulo...

Open access Research Article 10.9734/ajb2t/2025/v11i4264