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Muhammad Sohail S. Mirza

Publications (9)

Comparative Efficacy of Anti-tumor Necrosis Factor (TNF) Therapy in Inducing and Maintaining Remission from Crohn's Disease: A Systematic Review and Meta-analysis

Muhammad Sohail S. Mirza, Maria Khan, Md S. Rahman, Ayman Nadeem, Goutham R. Anugu, Mohd Diya Masmoum, Zainab Hameed, Muhammad H. Khawar & Muzafar Mansoor · Journal of Advances in Medicine and Medical Research · 2024

Background: Anti-TNF agents have emerged not only as inducers of remission but have also shown clinical efficacy in the maintenance of remission in patients suffering from Inflammatory Bowel Disease. However, there is limited quantitative evidence of their effectiveness in Crohn’...

Open access Research Article 10.9734/jammr/2024/v36i95561

The Role of Comorbidities in Opioid Overdose Risk: A Systematic Review

Raheel Chaudhry, Ghazala S. Virk, Imdad Ullah, Muhammad Sohail S. Mirza, Mehwish Aqueel & Riaz Ghori · Journal of Advances in Medicine and Medical Research · 2025

The opioid overdose crisis has escalated into an international public health emergency, with mortality rates continuing to rise, a trend that was further intensified during the COVID-19 pandemic. Individuals with mental health conditions such as anxiety, depression, and thought d...

Open access Research Article 10.9734/jammr/2025/v37i45778

Management Strategies for Heart Failure with Preserved Ejection Fraction (HFpEF): A Systematic Review and Meta-analysis

Raheel Chaudhry, Arhum Mahmood, Akbar Khan, Muhammad Sohail S. Mirza, Rubela Ray, Kainat Asif & Hasher Khan · Journal of Advances in Medicine and Medical Research · 2024

Background: Heart failure with preserved ejection. Fraction is a set of clinical symptoms that raises mortality and morbidity. It should be addressed promptly and appropriately. Aims: The current systematic review examines management strategies for heart failure patients with pre...

Open access Research Article 10.9734/jammr/2024/v36i55439

Complications of Diabetes: Cardiovascular, Renal, and Neurological Implications

Mohamed Aboelmaaty, Huseyin Erdem AK, Nithish Gaddam, Mehwish Aqueel, Masood Ahmed, Muhammad Sohail S. Mirza & Kholood Ahmed · Journal of Advances in Medicine and Medical Research · 2025

Diabetes mellitus poses significant health challenges primarily due to its severe complications affecting the cardiovascular, renal, and nervous systems. Chronic hyperglycemia drives these complications through mechanisms like oxidative stress, inflammation, and the formation of...

Open access Research Article 10.9734/jammr/2025/v37i65855

Myocardial Infarction: Causes, Symptoms, and Emergency Response

Shazain Khan, Raheel Chaudhry, Arhum Mahmood, Mohd. Diya Masmoum, Shaf A. Altaf & Muhammad Sohail S. Mirza · Journal of Advances in Medicine and Medical Research · 2024

Myocardial infarction (MI), often known as a heart attack, is a severe form of coronary artery disease that causes myocardial damage or necrosis as a result of persistent ischemia. Hypertension, atherosclerosis, diabetes, hyperlipidemia, smoking, lack of physical activity, and ob...

Open access Research Article 10.9734/jammr/2024/v36i85527

Type 1 Diabetes Mellitus: Autoimmune Mechanisms and Treatment

Mustafa Moazam, Shazain Khan, Issac Quiroga, Karen Parra, Paulina Flores, Eman Fatima, Andrea Amato, Syeda I. Tahera & Muhammad Sohail S. Mirza · Journal of Advances in Medicine and Medical Research · 2024

This article provides a comprehensive overview of Type 1 Diabetes Mellitus (T1DM), highlighting the autoimmune origins of the illness and its therapeutic options. It discusses the role of insulin in metabolism and highlights the fact that the autoimmune destruction of pancreatic...

Open access Research Article 10.9734/jammr/2024/v36i75492

Efficacy of Proton Pump Inhibitors vs. H2 Receptor Antagonists in Managing GERD: A Systematic Review and Meta-Analysis

Ghazala S. Virk, Sarah Hack, Hemamalini Anand Murugesan, Pendyala Seetharam, Mahnoor Shah, Sana Afzal, Muhammad Hassan Saleem, Izzat Izzat, Masood Ahmed & Muhammad Sohail S. Mirza · Journal of Advances in Medicine and Medical Research · 2025

This systematic review and meta-analysis aimed to compare proton pump inhibitors (PPIs) and H2 receptor antagonists (H2RAs) in treating gastroesophageal reflux disease (GERD), with a focus on symptom resolution and esophagus lining recovery. Out of a total of 10 studies on sympto...

Open access Research Article 10.9734/jammr/2025/v37i45805

Breaking the Antibiotic Habit: Shorter Treatments for Complicated Appendicitis

Ayman Nadeem, Sandra Abdelmessih, Dinesh K. Eetala, Jagadeeswar R. Peddapati, Ashritha Vanakuri, Syed Muhammad Rehman Shah, Kashif Uddin Ahmed, Mohammad Z. Natt, FNU Fatima & Muhammad Sohail S. Mirza · Journal of Advances in Medicine and Medical Research · 2024

Background: Patients with acute complicated appendicitis, including gangrenous or perforated appendicitis and/or the presence of an abscess formation, usually require surgery followed by antibiotics. The optimal duration of antibiotic therapy for those infections is debatable; pr...

Open access Research Article 10.9734/jammr/2024/v36i105606

Impact of Omega-3 Fatty Acids on Cardiovascular Disease Prevention: an updated Meta-analysis of RCTs

Md S. Rahman, Waqas A. Usmani, Uzma Nureen, Ashraf Ullah, Mohd Diya Masmoum, Zaghum Abbas, Raneem Masmoum, Surya A. Palasani, Ali Noor & Muhammad Sohail S. Mirza · Journal of Advances in Medicine and Medical Research · 2024

Background: Omega-3 fatty acids have been extensively studied for their potential role in cardiovascular disease (CVD) prevention. This meta-analysis aims to provide an updated synthesis of data from randomized controlled trials (RCTs) to assess the efficacy of omega-3 supplement...

Open access Research Article 10.9734/jammr/2024/v36i95572