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N. C. Azubuike

Publications (6)

Evaluation of Vernonia amygdalina Leaves for Gastroprotective Activity on Experimental Models of Gastric Ulcer in Rats

N. C. Azubuike, O. S. Onwukwe, M. C. Ugwuodo & M. Toni-Duruaku · Journal of Complementary and Alternative Medical Research · 2022

Background: Vernonia amygdalina del. (Arecaceae) leaf, popularly known as ‘Bitter leaf’ is widely used as a leafy vegetable in soups and in folkloric medicine against many ailments including stomach discomfort. Aim: The current study aimed to assess the gastroprotective effect of...

Open access Research Article 10.9734/jocamr/2022/v19i2386

Alleviation of Acetic Acid-Induced Ulcerative Colitis in Rat Model by Vernonia amygdalina (Asteraceae) Leaf Extract

N. C. Azubuike & F. U. Nzenwa · Asian Journal of Research and Reports in Gastroenterology · 2022

Background: Ulcerative colitis (UC) is a category of chronic inflammatory intestinal disease of unknown origin. Some medicinal plants have been used as therapeutic targets for UC, however, there is a paucity of information on the use of Vernonia amygdalina leaves. Aim: The presen...

Open access Research Article

Evaluation of the Effect of Date Palm [Phoenix dactylifera] Fruit Extract on Methotrexate-Induced Reproductive Toxicity in Male Rats

N. C. Azubuike & C. C. Opoh · Journal of Complementary and Alternative Medical Research · 2022

Background: Phoenix dactylifera L. in the Palmae family (Arecaceae) is commonly known as Date palm. Its fruit is popularly consumed as food and also used as a herbal remedy for fertility enhancing effects in males. Aim: The present study was designed to explore the effect of P. d...

Open access Research Article 10.9734/jocamr/2022/v17i430339

Evaluation of Changes in Biochemical and Haematological Parameters of Albino Rats Following Subacute Oral Administration of Cinnamomum cassia (Cinnamon) Extract

C. N. Okwuosa, N. C. Azubuike & C. P. Okorie · Annual Research & Review in Biology · 2021

Background: Cinnamomum cassia stem bark is used traditionally for the treatment of digestive disorders, diabetes and to alleviate symptoms of cold or flu. Aim: The present study evaluated biochemical and haematological changes in male albino rats after exposure to the stem bark e...

Open access Research Article 10.9734/arrb/2021/v36i630393

Impact of Alcohol Intoxication on Pregnant Albino Wistar Rats; Some Blood Profile and Histopathological Evidence

A. O. Onyemelukwe, P. U. Achukwu, N. C. Azubuike, S. I. Ogenyi, O. S. Onwukwe, O. F. Odo & C. O. Ogu · Annual Research & Review in Biology · 2020

Aim: To investigate the effects of alcohol consumption on serum biochemistry and histomorphology of liver, kidneys and uterus of pregnant Albino Wistar rats. Study Design: An experimental study which lasted for six weeks was conducted in the Animal house of the Department of Phys...

Open access Research Article 10.9734/arrb/2020/v35i130175

Assessment of the Sub-acute Toxicity Profile of Vitex doniana (Sweet) Leaf Fractions on Albino Rats

O. S. Onwukwe, J. N. Ukwuani, A. O. Onyemelukwe, N. C. Azubuike, A. C. Onuba, O. C. Ogu, O. F. Odo & P. U. Achukwu · Annual Research & Review in Biology · 2020

Aim: To evaluate the sub-acute toxicity profile of fractions of Vitex doniana using adult albino rats. Study Design: An experimental study that lasted for 28 days. Place and Duration of Study: Department of Medical Laboratory Sciences and Animal House Unit, College of Medicine, U...

Open access Research Article 10.9734/arrb/2020/v35i230192