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Natalya Urakova

Publications (4)

Reprofiling Hydrogen Peroxide from Antiseptics to Pyolytics: A Narrative Overview of the History of Inventions in Russia

Aleksandr Urakov, Natalya Urakova, Alexey Reshetnikov, Albina Shchemeleva, Petr Shabanov, Lubov Lovtsova, Aleksandr Samorodov, Evgeny Fisher, Anastasia Stolyarenko, Daria Suntsova, Ilnur Yagudin & Nikita Muhutdinov · Journal of Pharmaceutical Research International · 2023

Pyolytics are drugs that dissolve thick pus when applied topically. This group of drugs was discovered in early 21st century in Russia as a result of successful repurposing of antiseptics hydrogen peroxide, sodium bicarbonate and sodium chloride from antiseptics to pyolytics. Pri...

Open access Research Article 10.9734/jpri/2023/v35i67333

Post-injection Complications. Nicolau Syndrome as a Consequence of Local Irritant Effects of Drugs, Including Antiseptics, Local Anesthetics, NSAIDs, Steroids and Anticoagulants

Aleksandr Urakov, Natalya Urakova, Evgeny Fisher, Ilnur Bashirov, Sabina Nurlanova, Anastasia Klimovich, Albina Fakhretdinova, Anvar Bakirov, Regina Balametova & Aleksandr Samorodov · Journal of Pharmaceutical Research International · 2022

It has been shown that some drugs considered to be of good quality today can cause an iatrogenic disease known as Nicolau syndrome. Nicolau syndrome is a rare cutaneous drug reaction occurring after injection many drugs. This disease has been found to be caused by the very strong...

Open access Research Article 10.9734/jpri/2022/v34i33A36123

Inflammation, Infiltration, Necrosis, Abscess and Nicolau Syndrome after Injection of Nonsteroidal Anti-inflammatory Drugs: What is the Reason?

Aleksandr Urakov & Natalya Urakova · Journal of Pharmaceutical Research International · 2022

It has been established that some nonsteroidal anti-inflammatory drugs (NSAIDs) when administered through injectable preparations have a local irritating effect, even though the preparations are considered high-quality. It seems that this local irritant action is not related to a...

Open access Research Article 10.9734/jpri/2022/v34i19A35803

Osmotic Activity of Drugs is an Important Factor of Their Local Action at the Injection Site: What We Don't Use to Prevent Post-Injection Abscesses

Aleksandr Urakov & Natalya Urakova · Journal of Pharmaceutical Research International · 2021

It is established that very few modern high-quality drugs in the dosage form "Solution for injection" have isoosmotic activity in the range of 280-300 mosmol/l of water. The main part of solutions for injection is hypotonic or hypertonic solutions, which can have osmotic activity...

Open access Research Article 10.9734/jpri/2021/v33i59B34428