Norman E. Buroker

VEGFA SNPs (rs34357231 & rs35569394), Transcriptional Factor Binding Sites and Human Disease

Norman E. Buroker · Journal of Advances in Medicine and Medical Research · 2015

Purpose: The human vascular endothelial growth factor (VEGF)-A gene transcribes a signaling protein involved in the regulation of angiogenesis, vasculogenesis and endothelial cell growth.  Two insertion/deletion (I/D) simple nucleotide polymorphisms (SNPs, rs34357231 & rs3556...

Open access Research Article 10.9734/BJMMR/2015/19777

Computational DIO2 rSNP Analysis, Transcriptional Factor Binding Sites and Disease

Norman E. Buroker · Journal of Advances in Medicine and Medical Research · 2015

Purpose: The DIO2 gene transcribes the deiodinase type 2 enzyme that changes the thyroid prohormone, thyroxine (T4), to the biologically active triiodothyronine (T3) hormone. T3 plays a vital part in the regulation of energy balance and glucose metabolism. DIO2 single-nucleotide...

Open access Research Article 10.9734/BJMMR/2015/18535