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Ogochi Blessing Chukwuneke

0009-0002-8034-2969

Publications (3)

CRISPR Gene Editing Strategies for Targeting Oncogene Addiction in Colorectal Cancer

Fortune Itoje Ebiala, Jumoke Ologun, John Kelenna Iregbu, Ogochi Blessing Chukwuneke, Aliaa Mohammed Mahmoud Soliman, Ayo Ebunolorun Ibukunoluwa, Rasheedat A. Busari MD, Oluwatobiloba Kehinde Adedokun & Lawrence John AJutor · Journal of Cancer and Tumor International · 2025

Background: Oncogene addiction occurs in most tumour cells it is a phenomenon capable of driving colorectal cancer (CRC) growth, where tumour cells rely on genes like KRAS, BRAF, or MYC to survive. This has been so far seen as an exploitable target for precision therapies. Aim: T...

Open access Research Article 10.9734/jcti/2025/v15i3316

Artificial Intelligence in Cancer Epigenetics: A Review of How Machine Learning Is Revealing New Patterns Beyond DNA Mutations

Fortune Itoje Ebiala, Cecilia Chika Unegbu, Precious Oluwamosope OKUNOLA, Ogochi Blessing Chukwuneke, Ololade Funke Olaitan, Ndubisi Ubaka Edebeatu & Damilola Ayodele Ojo · Journal of Cancer and Tumor International · 2025

Beyond the human genetic codes, epigenetics also plays a key role in regulating how genes are expressed. While mutations or genes are known to be major causes of cancer, Epigenetic alterations, including DNA methylation, histone modifications, and non-coding RNAs, play critical r...

Open access Research Article 10.9734/jcti/2025/v15i3317

The Role of Gut Microbiome in Autism Spectrum Disorder (ASD) and Emerging Treatment Strategies

Raphael Ijeokwu, Simran Goraya, Hassan Muhammed Ul Haq, Rufus Okocha, Roshan Goswami, Elijah Oluwasegun Ayoigbala Adetunji, Mohammed Nawazuddin, Oghenerukevwe Faith Ohwodo, Shazia Noreen Durrani, Ayesha Taqi, Ademilua Oluwatobi Iyanuoluwa, Andeebia Ayub Khan, Olasumbo Elizabeth Fagbenle, Ogochi Blessing Chukwuneke, Patrick Batti & Jovita Echere · Journal of Advances in Medicine and Medical Research · 2024

Autism spectrum disorder (ASD) is a neurodevelopmental disorder. It is distinguished by repetitive behaviors, trouble in social interaction, and difficulty in communication. Recent research has demonstrated a strong association between gut microbiota and ASD. The purpose of this...

Open access Research Article 10.9734/jammr/2024/v36i105593