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Owen R. Thornton

Publications (15)

Bulimia Nervosa Causing Unknown Threat to Oral Health: A Comprehensive Review

Owen R. Thornton & Wenjun Li · International Neuropsychiatric Disease Journal · 2025

Bulimia nervosa (BN) is a severe psychiatric disorder characterized by recurrent episodes of binge eating followed by compensatory behaviors, such as self-induced vomiting, misuse of laxatives, and excessive exercise. The oral and dental repercussions of BN can be profound, and d...

Open access Research Article 10.9734/indj/2025/v22i3493

The Psychology and Psychopathology of Ultrarunning: Mental Health and Psychiatric Insights into Extreme Endurance Athletes

Owen R. Thornton & Wenjun Li · International Neuropsychiatric Disease Journal · 2025

Ultrarunning, characterized by covering distances beyond the standard 42.195 km marathon, has emerged as a compelling model for exploring the interplay between extreme endurance performance and mental health. Recent ultrarunning psychology research underscores that these athletes...

Open access Research Article 10.9734/indj/2025/v22i1463

Global Trends and Correlations in Mental Health Disorders: A Comprehensive Analysis from 1990 to 2019

Owen R. Thornton & Wenjun Li · International Neuropsychiatric Disease Journal · 2024

This original paper aims to provide a comprehensive analysis of the prevalence and trends in mental health disorders (n=6,420) from 1990 to 2019. Utilizing a sourced dataset, statistical methods are used to explore the increasing rates of mental health disorders, with a focus on...

Open access Research Article 10.9734/indj/2024/v21i2425

Brain-Derived Neurotrophic Factor (BDNF) in Depression: A Mini Review of Clinical and Preclinical Evidence

Owen R. Thornton · International Neuropsychiatric Disease Journal · 2023

Depression is a complex psychiatric disorder that significantly impacts millions of individuals worldwide. Despite advances in our understanding of its neurobiological underpinnings, treatment options remain limited, and not all patients respond adequately to available therapies....

Open access Research Article 10.9734/indj/2023/v20i3399

The Role of the Hippocampus in Borderline Personality Disorder: Structural and Functional Abnormalities

Owen R. Thornton, Wenjun Li, Hunter Cole & Isabella Cólon · International Neuropsychiatric Disease Journal · 2023

This review article discusses the structural and functional abnormalities observed in the hippocampus of individuals with borderline personality disorder (BPD). The hippocampus plays a critical role in regulating emotions and memories, which has been implicated in the pathophysio...

Open access Research Article 10.9734/indj/2023/v19i2370

Varying Levels of Carbohydrate and Fat Diets for Ultramarathon Running: A Review on Performance and Health Outcomes

Owen R. Thornton · Asian Journal of Food Research and Nutrition · 2023

This literature review analyzed 20 studies (n=147) investigating the effects of a high-fat diet on ultrarunning performance and metabolism. Results suggest that a high-fat diet can improve fat oxidation during exercise and may improve ultrarunning performance in some cases, altho...

Open access Research Article

Borderline Personality Disorder and Neuroplasticity: A Review

Owen R. Thornton, Wenjun Li, Hunter Cole & Isabella Cólon · International Neuropsychiatric Disease Journal · 2023

Borderline Personality Disorder (BPD) is a challenging and complex mental health disorder characterized by emotional dysregulation, impulsivity, unstable relationships, and a poor sense of self. Neuroplasticity, the brain's ability to change and adapt in response to experiences,...

Open access Research Article 10.9734/indj/2023/v19i2367

Revolutionizing Arthritis Treatment: The Synergy of iPSCs and Extracellular Vesicles-based Acellular Therapies for Joint Tissue Repair

Owen R. Thornton & Wenjun Li · Asian Journal of Orthopaedic Research · 2022

This review discusses the current state of arthritis treatment and the limitations associated with traditional approaches. The review then explores the potential of induced pluripotent stem cells (iPSCs) and extracellular vesicles (EVs) for joint tissue repair. The use of iPSCs a...

Open access Research Article

Current Status of Lung Cancer Research

M. D. Jawad Noor, Owen R. Thornton & Kimberly Morton Cuthrell · International Research Journal of Oncology · 2023

One of the most common cancers to cause death worldwide is lung cancer. Lung carcinoma, another name for lung cancer, is a malignant lung tumor that is characterized by unchecked cell proliferation in lung tissues. This tumor has the potential to metastasize, or expand outside of...

Open access Research Article