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P. R. C. Esegbue

Publications (11)

Reversibility, Body Weight and Histo-architectural Alterations in the Anterior Pituitary Gland of Aqueous Azadirachta indica Extract Fed Wistar Rats

P. R. C. Esegbue, A. J. Uyovwiesevwa, G. T. Olowe & O. A. Udi · Asian Journal of Advanced Research and Reports · 2019

Several studies have reported the importance of neem plant (Azadirachta indica) with results showing it to be both medicinal and pharmacological in the property. However, little or no available record(s) relates its effect on body weights and the anterior pituitary gland. Consequ...

Open access Research Article 10.9734/ajarr/2019/v6i430157

Variations in Electrolyte and Salivary Amylase (Ptyalin) Levels in HIV-Positive Subjects

P. R. C. Esegbue, G. T. Olowe, B. O. Pereye & L. O. Ogagayere · International STD Research & Reviews · 2018

Not only has studies shown oral saliva as veritable in the maintenance of health state of the oral cavity, it has been asserted that salivary fluid composition levels may be important diagnostic tools for numerous ailments, including the Human Immunodeficiency Virus (HIV). Curren...

Open access Research Article 10.9734/ISRR/2018/45427

Biomarkers of Oxidative Stress Changes in Dose-Dependent Manner, Following Periodic Administration of Coffee and Caffeine

P. R. C. Esegbue, A. A. Aigbiremolen, R. A. Akindele, R. E. Ubom, O. M. Odigie, J. C. Igweh & C. P. Aloamaka · Asian Journal of Medical Principles and Clinical Practice · 2017

Scientifically called Coffea Arabica, Research interests in Coffee have expanded with the discovery of its antioxidant properties. Coffee is a popular beverage consumed worldwide. Its effect on health has been a global puzzle. In this study, the effect that coffee consumption has...

Open access Research Article

Coffee and Caffeine Consumption in Reproductive Functions of Adult Wistar Rats

P. R. C. Esegbue, A. A. Aigbiremolen, R. A. Akindele, O. D. Ehiwe, O. M. Odigie, A. O. Naiho & J. C. Igweh · International Journal of Biochemistry Research & Review · 2017

Coffee from Coffea arabica is a popular beverage consumed worldwide. Its effect on health has been a global puzzle. In this study, the effect of coffee and caffeine consumption on some reproductive structures and functions of Wistar rats were investigated. A hundred and seventy-f...

Open access Research Article 10.9734/IJBCRR/2017/30912

Arterial Blood Flow and its Association with BMI in Hypertensive Adult Male Subjects under Resting State

A. A. Aigbiremolen, P. R. C. Esegbue, R. E. Ubom, O. M. Odigie, I. O. Iribhogbe & C. P. Aloamaka · Journal of Advances in Medicine and Medical Research · 2018

The goal of this study was to determine the association between arterial blood flow in normal and high BMI of hypertensive adult male subjects under resting state. To achieve this, 400 humans were ethically recruited from Irrua Specialist Teaching hospital, Irrua, Edo State of Ni...

Open access Research Article 10.9734/JAMMR/2017/36815

Correlative Studies on Anthropometric Indexes for Identifying Obesity in Pregnancy

J. C. Igweh, P. R. C. Esegbue, A. A. Aigbiremolen, R. N. Ativie, E. M. Aisuodionoe, O. M. Odigie & C. E. Okereke · Journal of Advances in Medicine and Medical Research · 2017

Currently, Obesity in pregnancy is a major health problem across the globe. In the past 20 years, prevalence of Obesity in pregnancy has doubled, leading to a wide range of complications in pregnancy. To foretell and manage this condition, clinicians and other health practitioner...

Open access Research Article 10.9734/JAMMR/2017/28937

Modulations of Some Carbohydrate Metabolic Enzymes by Aqueous and Ethanol Buchholzia coriacea Seed Extract in Alloxan Induced Diabetic Rats

K. O. Gbagbeke, A. O. Naiho, P. R. C. Esegbue, M. O. Odigie & M. A. Omoirri · Asian Journal of Research in Biochemistry · 2018

Characterised by abnormal increase in blood glucose level, Diabetes is a metabolic disorder that is associated with complications in carbohydrate, protein and fat metabolism. In recent times, medicinal herbs have been implicated in traditional medical practice for the treatment o...

Open access Research Article 10.9734/ajrb/2018/v2i1402

Association between ABO, Rhesus Blood Groups, and Type II Diabetes Mellitus among the Urhobos

M. O. Ebeye, A. A. Aigbiremolen, P. R. C. Esegbue, R. E. Ubom, M. O. Odigie & J. C. Igweh · Asian Hematology Research Journal · 2018

Typing of red blood cells is a prerequisite for blood transfusion. Blood types (A, B, AB and O) may be respectively distributed and transmitted by Ethnicity and Mendelian heredity. The goal of this study was to determine amongst the Urhobos, the possible association between the A...

Open access Research Article

Alterations in Hepatic Functions in Administration of Pennisetum puerperium to Wistar Rats

Kelvin Asemota Enoma, Moses Aziakapono Omoirri, Ovwasa Felicia Tega, Olowe Gideon Temitope & P. R. C. Esegbue · International Research Journal of Gastroenterology and Hepatology · 2019

Part of its metabolic function, the liver; which is a vital organ of all vertebrates is exposed to numerous toxins that may alter its physiologic functions. This functional tendency is often implicated via specific markers whose levels can be assayed to ascertain the functional c...

Open access Research Article

Mitigations in Testicular, Hepatic, and Pancreatic Histo-morphology in Alloxan-induced Diabetic Sprague Rats Treated with Fresh Coconut Oil and Vitamin E

E. M. Aisuodionoe, A. O. Naiho, B. C. Okonkwo, G. T. Olowe, P. R. C. Esegbue & J. C. Igweh · Journal of Complementary and Alternative Medical Research · 2018

Diabetes Mellitus (DM) is a condition in which the pancreas produces insufficient amounts of insulin, or in which the body’s cells fail to respond appropriately to available insulin. In diabetics, glucose levels build up in the blood and urine, causing excessive urination, thirst...

Open access Research Article 10.9734/JOCAMR/2018/41581

Histomorphological and Thrombogenic Status of Wistar Rats Fed with Allium sativum (GARLIC) in Oxidative Stress Induced with Carbon Tetrachloride

I. K. Aromose, M. O. Ebeye, I. T. Ekwere, M. O. Odigie, P. R. C. Esegbue & J. C. Igweh · Asian Hematology Research Journal · 2018

Though concerns over the safety of medicinal drugs are following rife consumption of some herbal preparations, the underlying pathogenesis remains however cryptic. Awareness of the far-reaching effects of herbal preparations is germane to their continued use in traditional medici...

Open access Research Article