A Novel Single-Pot Process for the Efficient Synthesis of Nonivamide: Detailed Stoichiometric Engineering, Reaction Mechanism, and Comparative NMR Characterization with Capsaicin
Hemanth Kumar Manikyam, Sunil K. Joshi & P. Venkata Suresh · Journal of Scientific Research and Reports · 2026
Nonivamide (N-(4-hydroxy-3-methoxybenzyl) nonanamide), also known as pelargonic acid vanillylamide (PAVA), is an industrially important synthetic capsaicinoid with potent transient receptor potential vanilloid subtype-1 (TRPV1) agonistic activity and extensive applications in pha...
Open access
Research Article
10.9734/jsrr/2026/v32i94512