An Efficient Synthesis of 4-Aminomethyl-1-(2-Phenylethyl)-Piperidin-4-ol: A Key Intermediate in Fenspiride HCl Synthesis
Prasad Panchabhai, Neelakandan Kaliaperumal, Gopalakrishnan Mannathusamy & Anbuselvan Chinnadurai · Journal of Pharmaceutical Research International · 2021
The article confers a scalable manufacturing process of Fenspiride HCl. 4-aminomethyl-1-(2-phenylethyl)-piperidin-4-ol is the main building block in Fenspiride HCl synthesis. The reported reagents for 4-aminomethyl-1-(2-phenylethyl)-piperidin-4-ol synthesis are costly, explosive,...
Open access
Research Article
10.9734/jpri/2021/v33i51B33523