Prasant Noolu

Comparative Evaluation of Floating and Non-Floating Controlled-release Metformin HCl Tablets: In vitro and In vivo Characterization

Chinna Reddy Palem, Prasant Noolu, Praveen Rao Balguri, Nishanth Kumar Nagamalli & Sridhar Gumudevelli · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Objective: The present study aimed to comparatively evaluate floating and non-floating controlled-release formulations of Metformin HCl to understand the influence of formulation composition and processing variables on gastroretentive behavior, drug release characteristics, and p...

Open access Research Article 10.9734/ajrimps/2026/v15i2377

Sustained-Release Ophthalmic Drug Delivery Systems: An Updated Review of Innovations, Current Trends and Future Prospects

Chinna Reddy Palem, Vamshi Krishna Lekkala, Nishanth Kumar Nagamalli, Paidi Venkata Santhosh, Prasant Noolu & Sridhar Gumudevelli · Ophthalmology Research: An International Journal · 2026

Background & Scope: Ocular drug delivery is inherently limited by anatomical and physiological barriers such as rapid tear turnover, blinking, nasolacrimal drainage, and restricted corneal permeability. These protective mechanisms substantially reduce drug residence time and...

Open access Research Article 10.9734/or/2026/v21i2506