Design and Evaluation of Controlled-Release Floating Metformin HCl Tablets: Influence of Binder and Granulation Process on Buoyancy
Chinna Reddy Palem, Prashant Noolu, Varun Chilukoti, Praveen Rao Balguri, Nishanth Kumar Nagamalli & Sridhar Gumudevelli · Journal of Pharmaceutical Research International · 2025
Scope and objective: Objective of this study is to investigate how the combined effects of binder properties and granulation parameters shape the development and performance of controlled-release floating Metformin HCl tablets. It focuses on evaluating the suitability of various...