Amena Khatun Manica, Ejoke Akatugba, Kesiena Loveth Eguono, Fisayo Wasilat Adeyemo, Precious-Esther Ogechi Efuneshi, Pruthvirajsinh Rajendrasinh Solanki, Dhruvilkumar Narendrakumar Patel, Bernard Opeyemi Adedeji, Abraham Olayeri, Adeyemi Ogunbowale, Joshua Temitope Adekeye & Idris Oladimeji Junaid·International Journal of Biochemistry Research & Review·2025
DJ-1 (PARK7), a multifunctional protein implicated in both neurodegeneration and oncogenesis, remains an underexploited therapeutic target due to limitations in the structural and dynamic interrogation of its ligand-binding landscape. In this study, we employed an integrated comp...
Open access
Research Article10.9734/ijbcrr/2025/v34i61079
Winner Amaka Egejuru, Abel Ujaigbe Egbemhenghe, Bamidele Samson Omotara, Christiana Oluwaseun Aderemi, Ibidun Blessing Isaac, Emmanuel Parkay Oladokun, Pruthvirajsinh Rajendrasinh Solanki, Ihunanya Meejay Kanu, Christopher Ddamulira, Ibrahim Tope Abdulrasaq, Yemisi Elizabeth Asibor, Onyinyechi Vera Ofoegbu, Sheriff Olabisi Ogunyemi, Cyril Obaro Agadagba, Muhammad Qasim Ali & Olajide Enoch Aderemi·International Journal of Biochemistry Research & Review·2025
Aims: To identify potential small-molecule inhibitors of T-cell immunoglobulin and mucin domain-3 (TIM-3) through computational approaches and evaluate their interactions, stability, and structural dynamics. Study Design: A computational drug discovery study utilizing virtual scr...
Open access
Research Article10.9734/ijbcrr/2025/v34i1955