Small interference RNA (siRNA) is a double-stranded RNA of 21~25 nucleotides. siRNA functions using a natural phenomenon known as RNA interference (RNAi), a gene silencing mechanism. Hypothetically, siRNA can target and regulate the expression of any disease-related gene in a seq...
Open access
Research Article10.9734/jamps/2023/v25i1596
The CYP450 enzyme family is most responsible for the biotransformation of endobiotic and exobiotic. Eventually, this family will consist of the most abundant drug-metabolizing enzymes. Though the liver is the major metabolizing organ for drugs and xenobiotics, orally administered...
The induction of enzymes is a defensive mechanism for some xenobiotics, but it may alter the drug's safety and efficacy by altering the activity of metabolic enzymes. One of the major families of enzymes involved in phase I metabolism is Cytochrome P450 (CYP) enzymes which may ge...
Open access
Research Article10.9734/ibrr/2023/v14i1297
The global severity of COVID-19 remains high which results anxiety and other mental health problems, also it altered people's everyday lives, affected human connections and economic operations. The goal of this comprehensive review was to identify the effects of the linkage COVID...
Open access
Research Article10.9734/ajrid/2023/v12i4249