Azadirachta indica Natural Active Ingredients to Cure Mpox: In silico Targeting VP39
Maneesh Kumar, Suman Kumar, Ratnesh Kumar, Mithilesh Kumar Jha, Shashank Nand Tiwari & Pratima Gupta · Journal of Pharmaceutical Research International · 2025
VP39 is an essential enzyme in the Mpox virus acting as methyltransferase for RNA capping to translate viral mRNA during human infection. This enzyme adds a 7-methylguanosine cap at the 5' end of viral mRNAs, imitating the capping mechanism of the host cells to evade immune detec...
Open access
Research Article
10.9734/jpri/2025/v37i47676