Simon G. Patching

Polarising Agents and Spin Tags for Dynamic Nuclear Polarisation (DNP)-Enhanced Solid-State Nuclear Magnetic Resonance (ssNMR) Analysis of Biological Samples

Nighat Nawaz & Simon G. Patching · Current Journal of Applied Science and Technology · 2023

Solid-state nuclear magnetic resonance (ssNMR) spectroscopy can obtain structural, functional and ligand-binding information about frozen and solid-like biological samples. ssNMR spectra can be enhanced by orders of magnitude using the technique of dynamic nuclear polarisation (D...

Open access Research Article 10.9734/cjast/2023/v42i284197

Microscale Thermophoresis Analysis of Membrane Proteins

Nighat Nawaz, Roshan Ali, Muhammad Ali, Iain W. Manfield, Muhammad Kamran Taj, Mohammad Zahid Mustafa & Simon G. Patching · Chemical Science International Journal · 2024

Microscale thermophoresis (MST) is an analytical technique for measuring biomolecular interactions. It is based on the physical phenomenon that particles move within temperature gradients, which is affected by their size, charge, hydration shell and conformation. The MST sample m...

Open access Research Article 10.9734/CSJI/2024/v33i2887